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通过连续注射无水乙醇、1%聚多卡醇和凝血酶对食管静脉曲张进行硬化治疗。

Sclerotherapy of esophageal varices by consecutive injection of anhydrous ethanol: 1% polydocanol and thrombin.

作者信息

Kumagai Y, Makuuchi H, Yamazaki E

机构信息

Mitsukoshi Health and Welfare Foundation Clinic, Tokyo Japan.

出版信息

Surg Endosc. 1987;1(1):29-32. doi: 10.1007/BF00703084.

DOI:10.1007/BF00703084
PMID:3504050
Abstract

In 1978, the first Japanese report of sclerotherapy with the flexible esophagoscope was published. At the Second Meeting of the Japanese Society of Sclerotherapy for Esophageal Varices (August 1986), reports were given on over 4000 cases treated by over 70 groups of endoscopists using various methods and sclerosants. These cases included 15 (about 0.4%) in which esophageal perforation occurred, and other complications, some fatal, were also reported. The main problem is to reduce the frequency of these serious complications. Over 400 cases have been treated by the authors in the past 3 years with a method involving consecutive injections of anhydrous ethanol when it is certain that the needle is in the varices. If there is any possibility of the needle being dislocated, 3-5 ml 1% polydocanol is administered instead. Weekly injections should be repeated until all varices have been sclerosized. No major complications have been observed, and the results are satisfactory [7].

摘要

1978年,日本首次发表了关于使用可弯曲食管镜进行硬化治疗的报告。在日本食管静脉曲张硬化治疗学会第二次会议(1986年8月)上,有报告称70多个内镜医师小组采用各种方法和硬化剂治疗了4000多例病例。这些病例中有15例(约0.4%)发生了食管穿孔,还报告了其他一些并发症,其中有些是致命的。主要问题是降低这些严重并发症的发生率。在过去3年里,作者采用一种方法治疗了400多例病例,即当确定针头位于静脉曲张内时连续注射无水乙醇。如果针头有任何脱位的可能性,则改为注射3 - 5毫升1%的聚多卡醇。应每周重复注射,直到所有静脉曲张都被硬化。未观察到重大并发症,结果令人满意[7]。

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1
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Surg Endosc. 1987;1(1):29-32. doi: 10.1007/BF00703084.
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本文引用的文献

1
Treatment of oesophageal varices in portal hypertension by means of sclerosing injections.通过硬化剂注射治疗门静脉高压症中的食管静脉曲张。
Br Med J. 1955 Oct 8;2(4944):877-80. doi: 10.1136/bmj.2.4944.877.
2
Injection sclerotherapy of esophageal varices for patients undergoing emergency and elective surgery.对接受急诊和择期手术的患者进行食管静脉曲张硬化剂注射治疗。
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Prediction of variceal hemorrhage by esophageal endoscopy.通过食管内镜检查预测静脉曲张出血
水母基因组揭示了独特的同源盒基因簇和小 RNA 处理的保守性。
Nat Commun. 2020 Jun 19;11(1):3051. doi: 10.1038/s41467-020-16801-9.
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Whole-genome and time-course dual RNA-Seq analyses reveal chronic pathogenicity-related gene dynamics in the ginseng rusty root rot pathogen Ilyonectria robusta.全基因组和时间序列双重 RNA-Seq 分析揭示了人参锈腐病根腐病菌 Ilyonectria robusta 中与慢性致病性相关的基因动态。
Sci Rep. 2020 Jan 31;10(1):1586. doi: 10.1038/s41598-020-58342-7.
5
Foam sclerotherapy using polidocanol for balloon-occluded retrograde transvenous obliteration (BRTO).采用聚多卡醇泡沫硬化剂行球囊阻断逆行经静脉栓塞术(BRTO)。
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A review of 15 years' experience in the use of sclerotherapy in the control of acute haemorrhage from oesophageal varices.对15年使用硬化疗法控制食管静脉曲张急性出血经验的回顾。
Br J Surg. 1973 Oct;60(10):797-800. doi: 10.1002/bjs.1800601011.
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Outpatient endoscopic injection sclerosis of esophageal varices.门诊内镜下食管静脉曲张注射硬化治疗
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Endoscopic sclerotherapy: lessons from a necropsy study.
Gastrointest Endosc. 1986 Aug;32(4):269-73. doi: 10.1016/s0016-5107(86)71844-0.
7
Outpatient esophageal variceal sclerotherapy: safe and cost-effective. A prospective study.门诊食管静脉曲张硬化疗法:安全且具有成本效益。一项前瞻性研究。
Gastrointest Endosc. 1986 Feb;32(1):1-3. doi: 10.1016/s0016-5107(86)71717-3.