Garratt Richard C
São Carlos Institute of Physics, University of São Paulo, São Carlos, Brazil.
Biophys Rev. 2021 Nov 11;13(6):867-869. doi: 10.1007/s12551-021-00889-4. eCollection 2021 Dec.
A wide range of topics was raised by the four invited speakers who took part in the session on protein structure, dynamics, and function during the 20th IUPAB Congress. Most of the emphasis was placed on understanding the underlying biological phenomena of interest although applications in drug development were also mentioned. For both these purposes, it was clear that a complete description of the dynamics of the system was as important as the structures themselves. The subjects covered included antibiotic peptides, sodium channels, the synthesis of the bacterial cell wall, and protein dynamics using X-FELs.
在第20届国际纯粹与应用生物物理学联合会（IUPAB）大会期间，参加蛋白质结构、动力学和功能会议的四位特邀发言人提出了广泛的主题。尽管也提到了在药物开发中的应用，但大部分重点都放在了理解感兴趣的潜在生物学现象上。对于这两个目的而言，很明显系统动力学的完整描述与结构本身同样重要。涵盖的主题包括抗菌肽、钠通道、细菌细胞壁的合成以及使用X射线自由电子激光（X-FELs）研究蛋白质动力学。
