De Pace Doranna, Ariotti Sara, Persampieri Simone, Patti Giuseppe, Lupi Alessandro
Cardiology Division, Ospedale Unico Plurisede del VCO, Verbano-Cusio-Ossola, Italy.
Clinica Cardiologica, AOU Maggiore della Carità, Università del Piemonte Orientale, Novara, Italy.
Eur J Case Rep Intern Med. 2021 Dec 21;8(12):002854. doi: 10.12890/2021_002854. eCollection 2021.
SARS-CoV-2 infection is associated with an increased risk of venous thromboembolism (VTE), which is common during active illness but unusual in milder cases and after healing. We describe a case of bilateral acute pulmonary embolism occurring 3 months after recovery from a paucisymptomatic SARS-CoV-2 infection. The only VTE risk factor demonstrable was a history of previous SARS-CoV-2 infection, with laboratory signs of residual low-grade inflammation. Clinicians should be aware of VTE as a potential cause of sudden dyspnoea after COVID-19 resolution, especially in the presence of persistent systemic inflammation.
Venous thromboembolism may occur after COVID-19, even in milder SARS-CoV-2 infections and late after coronavirus clearance.Laboratory signs of systemic inflammation are clues for suspecting venous thromboembolism as a cause of sudden dyspnoea in patients with low risk scores for pulmonary embolism but with previous COVID-19 infection.
新型冠状病毒2型（SARS-CoV-2）感染与静脉血栓栓塞（VTE）风险增加相关，VTE在疾病活动期常见，但在轻症病例及康复后不常见。我们描述了1例在无症状的SARS-CoV-2感染康复3个月后发生双侧急性肺栓塞的病例。唯一可证实的VTE危险因素是既往SARS-CoV-2感染史，伴有残余低度炎症的实验室指标。临床医生应意识到VTE是COVID-19缓解后突发呼吸困难的潜在原因，尤其是在存在持续性全身炎症的情况下。
COVID-19后可能发生静脉血栓栓塞，即使在轻症SARS-CoV-2感染及冠状病毒清除后较晚时也可能发生。全身炎症的实验室指标是怀疑静脉血栓栓塞是肺栓塞风险评分低但有既往COVID-19感染的患者突发呼吸困难原因的线索。
