Department of Pharmacology, Xiangnan University, Chenzhou, China.
Nat Prod Res. 2023 May;37(9):1573-1576. doi: 10.1080/14786419.2021.2023144. Epub 2022 Jan 25.
Mill. is a deciduous shrub, belonging to the Rhamnaceae family. Phytochemical investigation of seeds showed the presence of three undescribed 8,4'-type oxyneolignans (). Their structures were elucidated by comprehensive spectroscopic analyses. All isolated compounds were tested for antitumor activity against two human hepatoma cells (Hep3B and HepG2) and exhibited moderate cytotoxicity (IC: 33.79-49.62 M).
槐米是一种落叶灌木，属于鼠李科。对种子的植物化学研究表明存在三种未被描述的 8,4'-型氧新木脂素（）。通过综合光谱分析阐明了它们的结构。所有分离得到的化合物均进行了抗两种人肝癌细胞（Hep3B 和 HepG2）的抗肿瘤活性测试，表现出中等细胞毒性（IC：33.79-49.62 μM）。
