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酸枣种子中的吲哚乙酸衍生物。

Indoleacetic acid derivatives from the seeds of Ziziphus jujuba var. spinosa.

作者信息

Li Min, Wang Yu, Tsoi Bun, Jin Xiao-jie, He Rong-Rong, Yao Xiao-jun, Dai Yi, Kurihara Hiroshi, Yao Xin-Sheng

机构信息

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, China.

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, China; Quality Assurance Center, North China Pharmaceutical Group Semisyntech Co., Ltd., Shijiazhuang 052165, China.

出版信息

Fitoterapia. 2014 Dec;99:48-55. doi: 10.1016/j.fitote.2014.09.001. Epub 2014 Sep 11.

Abstract

A pair of diastereoisomers, the N-glycosylated derivatives of dioxindole-3-hydroxy-3-acetic acid 1-2, and their conjugates with flavonoids 3-8, was isolated from the seeds of Ziziphus jujuba var. spinosa. Their structures were elucidated by NMR spectroscopic analyses, and the absolute configurations were determined by circular dichroism method. Compounds 3-10 were evaluated for the antioxidant capacity, using the radical absorbance capacity (ORAC) assay.

摘要

从酸枣种子中分离出一对非对映异构体,即二氧吲哚 - 3 - 羟基 - 3 - 乙酸1 - 2的N - 糖基化衍生物及其与黄酮类化合物的缀合物3 - 8。通过核磁共振光谱分析阐明了它们的结构,并采用圆二色性方法确定了绝对构型。使用自由基吸收能力(ORAC)测定法对化合物3 - 10的抗氧化能力进行了评估。

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