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病例报告:溃疡性真菌性喉气管炎突发致命性出血—— 1例儿科病例报告

Case Report: Sudden Fatal Hemorrhage in Ulcerative Fungal Laryngotracheitis-A Pediatric Case Report.

作者信息

Porzionato Andrea, Stocco Elena, Emmi Aron, Macchi Veronica, De Caro Raffaele

机构信息

Section of Human Anatomy, Department of Neuroscience, University of Padova, Padova, Italy.

出版信息

Front Pediatr. 2022 Jan 11;9:764027. doi: 10.3389/fped.2021.764027. eCollection 2021.

DOI:10.3389/fped.2021.764027
PMID:35087772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8787292/
Abstract

In this report, we describe an autopsy case of a child affected by acute lymphoblastic leukemia and opportunistic pulmonary aspergillosis. The patient died because of a full-thickness tracheal wall ulceration with right inferior thyroid artery lesion and sudden hemorrhage, likely ascribable to undiagnosed invasive laryngotracheitis. infection, particularly in immunocompromised patients, should be considered an urgent risk factor to manage as it may lead to sudden fatal events in absence of evident critical symptoms.

摘要

在本报告中,我们描述了一例患有急性淋巴细胞白血病并伴有机会性肺曲霉病的儿童尸检病例。患者死于全层气管壁溃疡伴右下甲状腺动脉病变及突然出血,这可能归因于未被诊断出的侵袭性喉气管炎。感染,尤其是在免疫功能低下的患者中,应被视为一个需要紧急处理的危险因素,因为在没有明显严重症状的情况下,它可能导致突然的致命事件。

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1
Case Report: Sudden Fatal Hemorrhage in Ulcerative Fungal Laryngotracheitis-A Pediatric Case Report.病例报告:溃疡性真菌性喉气管炎突发致命性出血—— 1例儿科病例报告
Front Pediatr. 2022 Jan 11;9:764027. doi: 10.3389/fped.2021.764027. eCollection 2021.
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An Med Interna. 1993 Jul;10(7):337-40.
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本文引用的文献

1
Primary aspergillosis of the larynx causing acute airway distress.喉原发性曲霉菌病致急性气道阻塞。
BMJ Case Rep. 2021 Apr 9;14(4):e240434. doi: 10.1136/bcr-2020-240434.
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Disseminated Infection in a Non-HIV Infant With a Homozygous Private Variant of .HIV 阴性婴儿携带纯合私有变异. 所致播散性感染
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Fungal infections in children with haematologic malignancies and stem cell transplant recipients.儿童血液恶性肿瘤和干细胞移植受者的真菌感染。
Br J Haematol. 2020 May;189(4):607-624. doi: 10.1111/bjh.16452. Epub 2020 Mar 11.
5
Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease.侵袭性气管支气管曲霉病伴支气管溃疡并发非结核分枝杆菌病
Intern Med. 2020 May 1;59(9):1189-1194. doi: 10.2169/internalmedicine.3827-19. Epub 2020 Feb 1.
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A Rare Case of Vocal Cord Aspergillosis.一例罕见的声带曲霉病病例。
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):868-871. doi: 10.1007/s12070-019-01626-w. Epub 2019 Feb 28.
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Application of Flow Cytometry in the Diagnostics Pipeline of Primary Immunodeficiencies Underlying Disseminated Infection in HIV-Negative Children.流式细胞术在 HIV 阴性儿童播散性感染相关原发性免疫缺陷症诊断中的应用。
Front Immunol. 2019 Sep 13;10:2189. doi: 10.3389/fimmu.2019.02189. eCollection 2019.
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Invasive tracheal aspergillosis after chemoradiotherapy treatment.放化疗治疗后发生的侵袭性气管曲霉病。
Respirol Case Rep. 2019 Aug 7;7(7):e00473. doi: 10.1002/rcr2.473. eCollection 2019 Oct.
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ESCMID-ECMM guideline: diagnosis and management of invasive aspergillosis in neonates and children.ESCMID-ECMM 指南:新生儿和儿童侵袭性曲霉病的诊断和管理。
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Challenges and Clinical Implications of the Diagnosis of Cytomegalovirus Lung Infection in Children.儿童巨细胞病毒肺部感染诊断的挑战与临床意义
Curr Infect Dis Rep. 2019 May 30;21(7):24. doi: 10.1007/s11908-019-0681-x.