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The interrelationships between antimicrobial resistance, COVID-19, past, and future pandemics.抗微生物药物耐药性、COVID-19 与过去和未来大流行之间的相互关系。
J Infect Public Health. 2021 Jan;14(1):53-60. doi: 10.1016/j.jiph.2020.10.018. Epub 2020 Dec 9.
2
Methicillin-Resistant (MRSA): One Health Perspective Approach to the Bacterium Epidemiology, Virulence Factors, Antibiotic-Resistance, and Zoonotic Impact.耐甲氧西林金黄色葡萄球菌(MRSA):从“同一健康”视角看该细菌的流行病学、毒力因子、抗生素耐药性及人畜共患病影响
Infect Drug Resist. 2020 Sep 22;13:3255-3265. doi: 10.2147/IDR.S272733. eCollection 2020.
3
Community pharmacy services and preparedness during COVID-19 outbreak in Madinah, Saudi Arabia.沙特阿拉伯麦地那在新冠疫情期间的社区药房服务与准备情况
Saudi Pharm J. 2020 Nov;28(11):1402-1407. doi: 10.1016/j.jsps.2020.09.004. Epub 2020 Sep 17.
4
COVID-19 and the potential long-term impact on antimicrobial resistance.COVID-19 与潜在的长期抗菌药物耐药性影响
J Antimicrob Chemother. 2020 Jul 1;75(7):1681-1684. doi: 10.1093/jac/dkaa194.
5
Coronavirus Disease 2019, Superinfections, and Antimicrobial Development: What Can We Expect?新型冠状病毒肺炎、合并感染与抗菌药物研发:我们有何期待?
Clin Infect Dis. 2020 Dec 17;71(10):2736-2743. doi: 10.1093/cid/ciaa524.
6
Understanding the risk of emerging bacterial resistance to over the counter antibiotics in topical sore throat medicines.了解非处方咽喉痛药物中潜在的细菌对抗生素耐药的风险。
J Appl Microbiol. 2020 Oct;129(4):916-925. doi: 10.1111/jam.14682. Epub 2020 May 26.
7
Community pharmacy sales of non-prescribed antibiotics in Riyadh, Saudi Arabia: a simulated patient study.沙特阿拉伯利雅得社区药房非处方抗生素销售情况:一项模拟患者研究。
Int J Clin Pharm. 2020 Apr;42(2):341-346. doi: 10.1007/s11096-020-01033-0. Epub 2020 Apr 16.
8
Clinical characteristics of 25 death cases with COVID-19: A retrospective review of medical records in a single medical center, Wuhan, China.25 例 COVID-19 死亡病例的临床特征:对中国武汉某单一医疗中心病历的回顾性研究。
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Providing pharmacy services during the coronavirus pandemic.在新冠疫情期间提供药学服务。
Int J Clin Pharm. 2020 Apr;42(2):299-304. doi: 10.1007/s11096-020-01017-0. Epub 2020 Mar 28.
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Antimicrobial resistance, mechanisms and its clinical significance.抗菌药物耐药性、机制及其临床意义。
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沙特阿拉伯社区药店在 COVID-19 疫情期间销售非处方抗生素:一项模拟患者研究。

Over-the-counter sale of antibiotics during COVID-19 outbreak by community pharmacies in Saudi Arabia: a simulated client study.

机构信息

Department of Clinical and Hospital Pharmacy, College of Pharmacy, Taibah University, P. O. Box 30051, Madinah, 41477, Kingdom of Saudi Arabia.

出版信息

BMC Health Serv Res. 2022 Jan 29;22(1):123. doi: 10.1186/s12913-022-07553-x.

DOI:10.1186/s12913-022-07553-x
PMID:35093049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8799453/
Abstract

BACKGROUND

Recent studies have reflected increased global concern regarding the possible acceleration of bacterial resistance secondary to the reported overuse and misuse of antibiotics during the COVID-19 pandemic. Therefore, this study aimed to investigate the nonprescribed sale of antibiotics by community pharmacies in Saudi Arabia during the COVID-19 outbreak and the pharmacists' skills in triaging COVID-19 suspects.

METHODS

Herein, 120 pharmacies were randomly selected and surveyed by simulated clients who presented gradual demands to convince the encountered pharmacists to agree to the over-the-counter sale of antibiotics. The pharmacists' responses and counseling skills were documented in addition to their effectiveness in triaging suspected COVID-19 cases.

RESULTS

Nineteen pharmacists (15.8%) were convinced to sell nonprescribed antibiotics after various levels of demand by clients. Moreover, twenty pharmacists (16.7%), who refused to sell nonprescribed antibiotics, referred the clients to clinics where they could easily obtain prescriptions, or to other pharmacies that violate the system. In addition, 29 pharmacists (24.2%) were not concerned about possible COVID-19 suspects, and 47-66 (39.2-55%) of them demonstrated different responses and recommendations. Moreover, 12 pharmacists of the 19 who violated the law did not offer any counseling regarding the use of the antibiotics.

CONCLUSIONS

The nonprescribed sale of antibiotics is still prevalent and may have increased during the COVID-19 outbreak in Saudi Arabia, thereby increasing the risk of accelerated bacterial resistance. The pharmacists' skills in triaging COVID-19 suspects and patient education and counseling were below expectations. Further follow-up studies are highly recommended.

摘要

背景

最近的研究反映出,由于在 COVID-19 大流行期间报告的抗生素过度使用和滥用,人们越来越担心细菌耐药性可能会加速。因此,本研究旨在调查沙特阿拉伯社区药房在 COVID-19 爆发期间非处方销售抗生素的情况,以及药剂师在分诊 COVID-19 疑似病例方面的技能。

方法

在此,通过模拟客户对 120 家随机选择的药店进行调查,模拟客户逐渐提出要求,以说服遇到的药剂师同意非处方销售抗生素。记录了药剂师的反应和咨询技巧,以及他们在分诊 COVID-19 疑似病例方面的有效性。

结果

在客户提出不同程度的需求后,有 19 名药剂师(15.8%)被说服出售非处方抗生素。此外,有 20 名药剂师(16.7%)拒绝出售非处方抗生素,他们将客户转介到可以轻松获得处方的诊所,或转介到其他违反系统的药店。此外,有 29 名药剂师(24.2%)对可能的 COVID-19 疑似病例不感兴趣,其中 47-66 名(39.2-55%)的药剂师表现出不同的反应和建议。此外,违反法律的 19 名药剂师中的 12 名没有提供任何关于抗生素使用的咨询。

结论

在沙特阿拉伯 COVID-19 爆发期间,非处方销售抗生素仍然很普遍,并且可能有所增加,从而增加了细菌耐药性加速的风险。药剂师在分诊 COVID-19 疑似病例以及患者教育和咨询方面的技能低于预期。强烈建议进行进一步的后续研究。