Department of Paediatrics, Tampere University Hospital, Tampere, Finland.
Tampere Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Acta Paediatr. 2022 May;111(5):979-984. doi: 10.1111/apa.16259. Epub 2022 Jan 31.
To retrospectively assess the indications for and findings on 24-hour electrocardiographic (Holter) monitoring in newborns, focussing on bradycardias and extrasystoles.
Data included 337 term-born infants. Holter indications were categorised into bradycardias below 80 beats per minute, extrasystoles, any tachycardia and other. Heart rate below 60 beats per minute, pathological atrioventricular conduction, supraventricular or ventricular tachycardia, or either atrial premature contractions over 10% or ventricular premature contractions over 5% of total beats were defined as significant arrhythmia on Holter.
The median age was 6 days (range: 2-62 days). Bradycardia (42%) or extrasystoles (32%) were the most common Holter indications. Fifty-three infants (16%) had significant arrhythmia on Holter. Heart disease or 12-lead electrocardiogram expressing extrasystoles or conduction abnormalities were associated with significant arrhythmias (p = 0.046 and p < 0.001, respectively). Twenty-seven of 109 infants (25%) with extrasystoles as a Holter indication had abnormal Holter results, but only seven (6.4%) had significant arrhythmia on Holter if the 12-lead electrocardiogram was normal. No pathology was found behind bradycardias below 80 beats per minute in the absence of heart disease.
Among term newborns with extrasystoles or bradycardias, Holter monitoring could be targeted to infants with heart disease or abnormal electrocardiograms.
回顾性评估 24 小时心电图(动态心电图)监测在新生儿中的适应证和结果,重点关注心动过缓和期外收缩。
纳入 337 例足月出生的婴儿。将动态心电图的适应证分为心动过缓(低于 80 次/分钟)、期外收缩、任何心动过速和其他。低于 60 次/分钟的心率、病理性房室传导、室上性或室性心动过速,或心房期前收缩超过总搏动的 10%或室性期前收缩超过总搏动的 5%,定义为动态心电图上的显著心律失常。
中位年龄为 6 天(范围:2-62 天)。心动过缓(42%)或期外收缩(32%)是最常见的动态心电图适应证。53 例婴儿(16%)在动态心电图上有显著心律失常。心脏病或 12 导联心电图表现出期外收缩或传导异常与显著心律失常相关(p=0.046 和 p<0.001)。27 例以期外收缩为动态心电图适应证的婴儿中,27 例(25%)的动态心电图结果异常,但如果 12 导联心电图正常,仅有 7 例(6.4%)在动态心电图上有显著心律失常。在没有心脏病的情况下,低于 80 次/分钟的心动过缓没有发现病理。
在有期外收缩或心动过缓的足月新生儿中,如果存在心脏病或心电图异常,可以针对婴儿进行动态心电图监测。