Xie Yuliang, Becker Ryan, Scott Michael, Bean Kayla, Huang Tony Jun
Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, 52242, United States.
Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27710, United States.
Engineering (Beijing). 2022 Jan 27. doi: 10.1016/j.eng.2022.01.003.
COVID-19, an infectious pulmonary disease caused by the SARS-CoV-2 virus, has profoundly impacted the world, motivating researchers across a broad spectrum of academic disciplines to gain a deeper understanding and develop effective therapies to this disease. This article presents an engineering perspective on how microfluidic technologies may address some of the challenges presented by COVID-19 and other pulmonary diseases. In particular, this article highlights urgent needs in pulmonary medicine, with an emphasis on technological innovations in the microfluidic manipulation of particles and fluids, and how these innovations may contribute to the study, diagnosis, and therapy of pulmonary diseases.
新冠病毒病（COVID-19）是由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的一种感染性肺部疾病，对全球产生了深远影响，促使广泛学术领域的研究人员更深入地了解该疾病并开发有效的治疗方法。本文从工程学角度探讨了微流控技术如何应对COVID-19和其他肺部疾病带来的一些挑战。特别是，本文强调了肺部医学的迫切需求，重点介绍了颗粒和流体微流控操作方面的技术创新，以及这些创新如何有助于肺部疾病的研究、诊断和治疗。
