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Machine learning for tumor growth inhibition: Interpretable predictive models for transparency and reproducibility.

作者信息

Meid Andreas D, Gerharz Alexander, Groll Andreas

机构信息

Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany.

Department of Statistics, TU Dortmund University, Dortmund, Germany.

出版信息

CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11(3):257-261. doi: 10.1002/psp4.12761. Epub 2022 Feb 1.

DOI:10.1002/psp4.12761
PMID:35104394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8923723/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6358/8923723/13abd9f8f044/PSP4-11-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6358/8923723/932896de72fe/PSP4-11-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6358/8923723/13abd9f8f044/PSP4-11-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6358/8923723/932896de72fe/PSP4-11-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6358/8923723/13abd9f8f044/PSP4-11-257-g002.jpg

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本文引用的文献

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Using the Causal Inference Framework to Support Individualized Drug Treatment Decisions Based on Observational Healthcare Data.使用因果推断框架,基于观察性医疗保健数据支持个性化药物治疗决策。
Clin Epidemiol. 2020 Nov 2;12:1223-1234. doi: 10.2147/CLEP.S274466. eCollection 2020.
3
Predictive approaches to heterogeneous treatment effects: a scoping review.
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CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11(3):262-263. doi: 10.1002/psp4.12760. Epub 2022 Jan 31.
预测异质治疗效果的方法:范围综述。
BMC Med Res Methodol. 2020 Oct 23;20(1):264. doi: 10.1186/s12874-020-01145-1.
4
A critical review of graphics for subgroup analyses in clinical trials.对临床试验亚组分析图表的批判性综述。
Pharm Stat. 2020 Sep;19(5):541-560. doi: 10.1002/pst.2012. Epub 2020 Mar 25.
5
Demonstrating Heterogeneity of Treatment Effects Among Patients: An Overlooked but Important Step Toward Precision Medicine.展示患者间治疗效果的异质性:迈向精准医学的被忽视但重要的一步。
Clin Pharmacol Ther. 2019 Jul;106(1):204-210. doi: 10.1002/cpt.1372. Epub 2019 Mar 12.
6
Model-Informed Drug Development: Current US Regulatory Practice and Future Considerations.模型引导药物研发:当前美国监管实践与未来考量
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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.阿特珠单抗对比多西他赛用于既往治疗过的非小细胞肺癌患者(OAK):一项3期、开放标签、多中心随机对照试验
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