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A metabolic perspective into antimicrobial tolerance and resistance.

作者信息

Bhusal Ram Prasad, Barr Jeremy J, Subedi Dinesh

机构信息

Monash Biomedicine Discovery Institute, and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

School of Biological Sciences, Monash University, Clayton, VIC 3800, Australia.

出版信息

Lancet Microbe. 2022 Mar;3(3):e160-e161. doi: 10.1016/S2666-5247(22)00006-4. Epub 2022 Jan 27.

DOI:10.1016/S2666-5247(22)00006-4
PMID:35106516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8794497/
Abstract
摘要

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J Am Chem Soc. 2021 Oct 27;143(42):17666-17676. doi: 10.1021/jacs.1c07970. Epub 2021 Oct 19.
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Itaconate is a covalent inhibitor of the isocitrate lyase.衣康酸是异柠檬酸裂解酶的共价抑制剂。
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Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study.全球、地区和国家脓毒症发病率和死亡率,1990-2017 年:全球疾病负担研究分析。
Lancet. 2020 Jan 18;395(10219):200-211. doi: 10.1016/S0140-6736(19)32989-7.
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Alternative fate of glyoxylate during acetate and hexadecane metabolism in Acinetobacter oleivorans DR1.在食油不动杆菌 DR1 中,乙酸盐和十六烷代谢过程中乙醛酸的替代命运。
Sci Rep. 2019 Oct 7;9(1):14402. doi: 10.1038/s41598-019-50852-3.
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Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in .糖异生前体的可用性调节. 中的乙醛酸支路通量。
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