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延迟抗生素处方策略的实施。初级保健中的前瞻性观察研究。

Implementation of the delayed antibiotic prescribing strategy. Prospective observation study in primary care.

机构信息

Carl Llor, University Institute in Primary Care Research Jordi Gol, Via Roma Health Centre, Barcelona, Gran Via de les Corts Catalanes, 497, atic - 08007 Barcelona, Spain.

出版信息

Rev Esp Quimioter. 2022 Apr;35(2):213-217. doi: 10.37201/req/141.2021. Epub 2022 Feb 3.

DOI:10.37201/req/141.2021
PMID:35109645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8972696/
Abstract

OBJECTIVE

We aimed to compare the actual consumption of antibiotics among patients issued delayed antibiotic prescribing with the consumption observed in a non-systematic review of studies on delayed prescribing.

METHODS

Observational study carried out in three primary care centres from September 2018 until March 2020. We tracked the electronic records of the 82 patients with episodes of acute bronchitis and 44 acute pharyngitis who were given a patient-led delayed prescription to determine whether the prescription was filled and when this medication was obtained.

RESULTS

The prescriptions were never filled in 50 cases (39.7%), but five patients took another antibiotic within the first two weeks. Out of 76 patients who did take the delayed prescription, only 12 obtained the medication based on the instructions given by the doctors (15.8%).

CONCLUSIONS

The strategy of delayed antibiotic prescribing resulted in a reduction in antibiotic use, but this reduction was lower than in randomised clinical trials, being comparable to the results obtained with other observational studies on delayed antibiotic prescribing. In addition, only a few patients adhered to the doctors' instructions.

摘要

目的

本研究旨在比较延迟开具抗生素医嘱的患者的实际抗生素使用情况与延迟开具医嘱相关研究的非系统性综述中的观察结果。

方法

本研究为 2018 年 9 月至 2020 年 3 月在三个初级保健中心进行的观察性研究。我们追踪了 82 例急性支气管炎和 44 例急性咽炎患者的电子病历,这些患者获得了患者主导的延迟处方,以确定处方是否被开具以及何时开具。

结果

50 例(39.7%)的处方从未被开具,但是有 5 名患者在头两周内使用了另一种抗生素。在 76 名服用延迟处方的患者中,只有 12 名患者根据医生的指示(15.8%)获得了药物。

结论

延迟开具抗生素医嘱的策略确实减少了抗生素的使用,但与随机临床试验相比,这种减少幅度较低,与其他延迟开具抗生素医嘱的观察性研究结果相当。此外,只有少数患者遵循了医生的指示。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/8972696/9ff6082147e1/revespquimioter-35-213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/8972696/9ff6082147e1/revespquimioter-35-213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56b6/8972696/9ff6082147e1/revespquimioter-35-213-g001.jpg

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