Kılıç Lütfiye, Altın Sedat, Gönenç Ortaköylü Mediha, Kanmaz Zehra Dilek, Tutar Tayjen, Özkan Gülcihan Zehra
Department of Chest Diseases, Koç University Hospital, İstanbul, Turkey.
Department of Chest Diseases, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.
Turk Thorac J. 2022 Jan;23(1):58-62. doi: 10.5152/TurkThoracJ.2022.21045.
Tuberculosis and COVID-19 diseases occur more frequently in people with similar risk factors. This study aimed to share the data on active tuberculosis patients during the severe acute respiratory syndrome coronavirus 2 pandemic.
The registration information of TB outpatient clinic between November 1, 2019, and April 20, 2020, was screened. A 7-question survey was administered to the patients who were diagnosed with active tuberculosis and who were agreed to participate in the study.
A total of 309 patients with active tuberculosis were evaluated, the average age of the patients was 42.5 ± 18.5 years, and 70% were male. The percentage of having at least 1 comorbidity was 30.4%. The percentage of coronavirus disease 2019 disease in our study population was 1.9%; none of the patients of coronavirus disease 2019 were taken into the intensive care unit or dead due to clinical deterioration and/or respiratory failure. On the other hand, in this process it was announced that 146 457 cases were diagnosed with coronavirus disease 2019 throughout the country, of which 72% had inpatient treatment, 2% died, and 944 patients were still being treated in the intensive care unit, of which 490 were intubated. The positivity ratio of the reverse transcription-polymerase chain reaction test was 20.0% in the study group, while 20.3% in the İstanbul population.
Tuberculosis patients might be more disadvantageous than the normal population in terms of the risk of exposure to severe acute respiratory syndrome coronavirus 2, but this does not cause an increase in the frequency and severity of coronavirus disease 2019 disease in active tuberculosis patients.
结核病和2019冠状病毒病在具有相似风险因素的人群中更为常见。本研究旨在分享严重急性呼吸综合征冠状病毒2大流行期间活动性肺结核患者的数据。
筛选2019年11月1日至2020年4月20日期间结核病门诊的登记信息。对被诊断为活动性肺结核且同意参与研究的患者进行了一项包含7个问题的调查。
共评估了309例活动性肺结核患者，患者的平均年龄为42.5±18.5岁，70%为男性。至少有一种合并症的患者比例为30.4%。我们研究人群中2019冠状病毒病的比例为1.9%；2019冠状病毒病患者中无一因临床恶化和/或呼吸衰竭而进入重症监护病房或死亡。另一方面，在此过程中宣布，全国共有146457例确诊为2019冠状病毒病，其中72%接受住院治疗，2%死亡，944例患者仍在重症监护病房接受治疗，其中490例进行了插管。研究组逆转录-聚合酶链反应检测的阳性率为20.0%，而伊斯坦布尔人群中的阳性率为20.3%。
结核病患者在接触严重急性呼吸综合征冠状病毒2的风险方面可能比正常人群更不利，但这并不会导致活动性肺结核患者中2019冠状病毒病的发病率和严重程度增加。
