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本文引用的文献

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British Thoracic Society Guideline for bronchiectasis in adults.英国胸科学会成人支气管扩张指南。
Thorax. 2019 Jan;74(Suppl 1):1-69. doi: 10.1136/thoraxjnl-2018-212463.
2
European Respiratory Society guidelines for the management of adult bronchiectasis.欧洲呼吸学会成人支气管扩张症管理指南。
Eur Respir J. 2017 Sep 9;50(3). doi: 10.1183/13993003.00629-2017. Print 2017 Sep.
3
Pregnancy among cystic fibrosis women in the era of CFTR modulators.CFTR 调节剂时代囊性纤维化女性的妊娠问题。
J Cyst Fibros. 2017 Nov;16(6):687-694. doi: 10.1016/j.jcf.2017.01.008. Epub 2017 Feb 10.
4
Pregnancy and cystic fibrosis: Approach to contemporary management.妊娠与囊性纤维化:当代管理方法
Obstet Med. 2014 Dec;7(4):147-55. doi: 10.1177/1753495X14554022. Epub 2014 Nov 7.
5
Pregnancy outcomes in the current era of cystic fibrosis care: a 15-year experience.当前囊性纤维化治疗时代的妊娠结局:15年经验
Aust N Z J Obstet Gynaecol. 2011 Jun;51(3):220-4. doi: 10.1111/j.1479-828X.2010.01287.x. Epub 2011 Feb 7.
6
Cystic fibrosis in pregnancy.妊娠期囊性纤维化
Clin Obstet Gynecol. 2010 Jun;53(2):369-76. doi: 10.1097/GRF.0b013e3181deb448.
7
Guidelines for the management of pregnancy in women with cystic fibrosis.囊性纤维化女性患者孕期管理指南。
J Cyst Fibros. 2008 Jan;7 Suppl 1:S2-32. doi: 10.1016/j.jcf.2007.10.001. Epub 2007 Nov 19.
8
Pregnancy in cystic fibrosis.囊性纤维化患者的妊娠
Curr Opin Pulm Med. 2007 Nov;13(6):537-40. doi: 10.1097/MCP.0b013e3282f01120.
9
Impact of pregnancy on women with cystic fibrosis.妊娠对囊性纤维化女性的影响。
Chest. 2006 Mar;129(3):706-11. doi: 10.1378/chest.129.3.706.
10
The effect of pregnancy on survival in women with cystic fibrosis.妊娠对囊性纤维化女性患者生存的影响。
Chest. 2003 Oct;124(4):1460-8. doi: 10.1378/chest.124.4.1460.

非囊性纤维化支气管扩张症患者孕期的母婴问题

Maternal and Fetal Problems in Patients with Non-Cystic Fibrosis Bronchiectasis During Pregnancy.

作者信息

Börekçi Şermin, Kubat Bahar, Senkardesler Gizem, Musellim Benan

机构信息

Department of Pulmonary Diseases, İstanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Turkey.

出版信息

Turk Thorac J. 2021 Jul;22(4):297-300. doi: 10.5152/TurkThoracJ.2021.20236.

DOI:10.5152/TurkThoracJ.2021.20236
PMID:35110246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8975312/
Abstract

OBJECTIVE

To detect the maternal and fetal problems experienced by patients with non-cystic fibrosis (non-CF) bronchiectasis during pregnancy.

MATERIAL AND METHODS

A total of 185 women aged over 18 years with medical records available, who were diagnosed as having non-CF bronchiectasis and followed in the outpatient clinic for bronchiectasis, were interviewed by phone between November 1, 2019 and December 31, 2019. Forty-seven women who accepted to participate, were able to understand and answer the survey, and had experienced at least 1 pregnancy, were included in the study, The survey questions were read and the answers were recorded. The same survey was administered to a control group of 95 women.

RESULTS

It was found that the number of patients experiencing an increase in at least 1 of the symptoms of cough, sputum production, and dyspnea during pregnancy, and the number of visits to emergency departments for respiratory conditions, were statistically significantly higher (P < .001 and P < .001, respectively), and the rate of live births was significantly lower (P = .009) in the non-CF bronchiectasis group compared with the control group. No significant difference was found between the groups in the number of miscarriages, preterm births, cesarean section, extra visits to the obstetrics department, and the presence of anomalies in the infants.

CONCLUSION

Among patients with non-CF bronchiectasis, it should be kept in mind that an increase may be seen in respiratory symptoms and the number of emergency department visits during pregnancy, and a decrease may be seen in the ratio of live births. These patients should be followed closely for these issues and measures should be taken accordingly.

摘要

目的

检测非囊性纤维化(非CF)支气管扩张症患者在孕期所经历的母婴问题。

材料与方法

2019年11月1日至2019年12月31日期间,通过电话访谈了185名年龄超过18岁、有病历记录、被诊断为非CF支气管扩张症且在门诊接受支气管扩张症随访的女性。47名同意参与、能够理解并回答调查问卷且至少经历过1次妊娠的女性被纳入研究。调查问卷的问题被读出并记录答案。对95名女性组成的对照组进行了相同的调查。

结果

发现非CF支气管扩张症组在孕期出现咳嗽、咳痰和呼吸困难中至少1种症状加重的患者数量以及因呼吸道疾病前往急诊科就诊的次数在统计学上显著更高(分别为P <.001和P <.001),与对照组相比,活产率显著更低(P =.009)。两组在流产、早产、剖宫产、额外前往产科就诊的次数以及婴儿是否存在异常方面未发现显著差异。

结论

对于非CF支气管扩张症患者,应记住孕期呼吸道症状可能加重,前往急诊科就诊的次数可能增加,活产率可能降低。应对这些问题密切关注这些患者并相应采取措施。