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非囊性纤维化支气管扩张症患者孕期的母婴问题

Maternal and Fetal Problems in Patients with Non-Cystic Fibrosis Bronchiectasis During Pregnancy.

作者信息

Börekçi Şermin, Kubat Bahar, Senkardesler Gizem, Musellim Benan

机构信息

Department of Pulmonary Diseases, İstanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Turkey.

出版信息

Turk Thorac J. 2021 Jul;22(4):297-300. doi: 10.5152/TurkThoracJ.2021.20236.

Abstract

OBJECTIVE

To detect the maternal and fetal problems experienced by patients with non-cystic fibrosis (non-CF) bronchiectasis during pregnancy.

MATERIAL AND METHODS

A total of 185 women aged over 18 years with medical records available, who were diagnosed as having non-CF bronchiectasis and followed in the outpatient clinic for bronchiectasis, were interviewed by phone between November 1, 2019 and December 31, 2019. Forty-seven women who accepted to participate, were able to understand and answer the survey, and had experienced at least 1 pregnancy, were included in the study, The survey questions were read and the answers were recorded. The same survey was administered to a control group of 95 women.

RESULTS

It was found that the number of patients experiencing an increase in at least 1 of the symptoms of cough, sputum production, and dyspnea during pregnancy, and the number of visits to emergency departments for respiratory conditions, were statistically significantly higher (P < .001 and P < .001, respectively), and the rate of live births was significantly lower (P = .009) in the non-CF bronchiectasis group compared with the control group. No significant difference was found between the groups in the number of miscarriages, preterm births, cesarean section, extra visits to the obstetrics department, and the presence of anomalies in the infants.

CONCLUSION

Among patients with non-CF bronchiectasis, it should be kept in mind that an increase may be seen in respiratory symptoms and the number of emergency department visits during pregnancy, and a decrease may be seen in the ratio of live births. These patients should be followed closely for these issues and measures should be taken accordingly.

摘要

目的

检测非囊性纤维化(非CF)支气管扩张症患者在孕期所经历的母婴问题。

材料与方法

2019年11月1日至2019年12月31日期间,通过电话访谈了185名年龄超过18岁、有病历记录、被诊断为非CF支气管扩张症且在门诊接受支气管扩张症随访的女性。47名同意参与、能够理解并回答调查问卷且至少经历过1次妊娠的女性被纳入研究。调查问卷的问题被读出并记录答案。对95名女性组成的对照组进行了相同的调查。

结果

发现非CF支气管扩张症组在孕期出现咳嗽、咳痰和呼吸困难中至少1种症状加重的患者数量以及因呼吸道疾病前往急诊科就诊的次数在统计学上显著更高(分别为P <.001和P <.001),与对照组相比,活产率显著更低(P =.009)。两组在流产、早产、剖宫产、额外前往产科就诊的次数以及婴儿是否存在异常方面未发现显著差异。

结论

对于非CF支气管扩张症患者,应记住孕期呼吸道症状可能加重,前往急诊科就诊的次数可能增加,活产率可能降低。应对这些问题密切关注这些患者并相应采取措施。

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