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立体定向放射外科治疗三叉神经痛改善了莫尔比昂综合征的症状。

Treatment of Trigeminal Neuralgia With Stereotactic Radiosurgery Improved Symptoms of Morbihan Syndrome.

作者信息

Burgess Laura, Mula-Hussain Layth, Malone Shawn

机构信息

Department of Radiology, Division of Radiation Oncology, University of Ottawa, Ottawa, CAN.

Department of Radiology, Division of Radiation Oncology, The Ottawa Hospital Research Institute, Ottawa, CAN.

出版信息

Cureus. 2021 Dec 28;13(12):e20774. doi: 10.7759/cureus.20774. eCollection 2021 Dec.

DOI:10.7759/cureus.20774
PMID:35111459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8793666/
Abstract

Trigeminal neuralgia (TN) is a neuropathic pain disorder characterized by paroxysmal pain in the maxillary and mandibular regions of the face. Morbihan syndrome is a disease that classically presents with dermatologic findings, including progressive facial edema and erythema. There are no previous reports of the onset of trigeminal neuralgia with Morbihan syndrome or previous reports describing improvement in symptoms of Morbihan syndrome with treatment of trigeminal neuralgia. We describe the case of a 62-year-old female who presented with trigeminal neuralgia and shortly thereafter developed significant facial edema and was diagnosed with Morbihan syndrome. The neuralgia was refractory to medical management and was effectively treated with stereotactic radiosurgery (SRS). This coincided with an improvement in her Morbihan syndrome that is now controlled following stereotactic radiosurgery and continued lymphatic massage.

摘要

三叉神经痛(TN)是一种神经性疼痛疾病,其特征为面部上颌和下颌区域的阵发性疼痛。莫尔比昂综合征是一种典型地表现出皮肤症状的疾病,包括进行性面部水肿和红斑。此前没有关于莫尔比昂综合征伴发三叉神经痛发作的报告,也没有关于通过治疗三叉神经痛改善莫尔比昂综合征症状的报告。我们描述了一名62岁女性的病例,该患者最初表现为三叉神经痛,此后不久出现明显的面部水肿,并被诊断为莫尔比昂综合征。该神经痛对药物治疗无效,经立体定向放射外科手术(SRS)有效治疗。这与她的莫尔比昂综合征的改善相吻合,目前在立体定向放射外科手术和持续的淋巴按摩后病情得到控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae5a/8793666/034e4059bae6/cureus-0013-00000020774-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae5a/8793666/034e4059bae6/cureus-0013-00000020774-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae5a/8793666/034e4059bae6/cureus-0013-00000020774-i01.jpg

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Treatment of Trigeminal Neuralgia With Stereotactic Radiosurgery Improved Symptoms of Morbihan Syndrome.立体定向放射外科治疗三叉神经痛改善了莫尔比昂综合征的症状。
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本文引用的文献

1
Unilateral Morbihan syndrome.单侧莫尔比昂综合征。
Dermatol Reports. 2021 Aug 5;14(2):9270. doi: 10.4081/dr.2021.9270. eCollection 2022 Jun 16.
2
Morbihan disease: A diagnostic dilemma: two cases with successful resolution.莫尔比昂病:诊断难题——两例成功解决的病例
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Trigeminal Neuralgia.三叉神经痛
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Successful treatment of solid persistent facial edema with isotretinoin and compression therapy.异维A酸与压迫疗法成功治疗持续性面部实性水肿
JAAD Case Rep. 2020 Jun 15;6(8):755-757. doi: 10.1016/j.jdcr.2020.06.013. eCollection 2020 Aug.
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Morbihan Syndrome, a UK Case Series.莫比汉综合征:英国病例系列研究
Ophthalmic Plast Reconstr Surg. 2020 Sep/Oct;36(5):438-443. doi: 10.1097/IOP.0000000000001589.
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Relationship of Inflammation With Trigeminal Neuralgia.炎症与三叉神经痛的关系。
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Effective Treatment of Morbihan's Disease with Long-term Isotretinoin: A Report of Three Cases.长期使用异维A酸有效治疗莫尔比昂病:三例报告
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Morbihan Disease Treatment: Two Case Reports and a Systematic Literature Review.莫比汉病治疗:两例病例报告和系统文献回顾。
Ophthalmic Plast Reconstr Surg. 2019 Mar/Apr;35(2):126-132. doi: 10.1097/IOP.0000000000001229.
10
Inflammation in the pathophysiology of neuropathic pain.神经病理性疼痛病理生理学中的炎症。
Pain. 2018 Mar;159(3):595-602. doi: 10.1097/j.pain.0000000000001122.