Effect of Probiotic Lactobacillus salivarius on Peri-Implantitis Pathogenic Bacteria: An In Vitro Study.

Background Varied treatment modalities have been described in the past for the management of peri-implant diseases but the evidence of the use of probiotics for the treatment of peri-implantitis is limited. The aim of this study was to determine the antagonistic growth effects of on the growth of peri-implantitis pathogens. Material and method Anin vitroassessment of probiotic on peri-implantitis pathogens was done using the serial tube dilution method. Minimum inhibitory concentration was calculated for five subgingival pathogens namely , , , , and Minimum inhibitory concentration (MIC) is defined as the lowermost concentration of any drug that prevents the noticeable growth of the test organism. In vitro assessment to determine the MIC is necessary for an in vivo application. The MIC value will also help to find the drug's accurate dosage. Results Peri-implantitis pathogens were cultured from individuals diagnosed with peri-implantitis. Except for all other pathogens were susceptible to the probiotic. had the lowest MIC (0.8mg/mL). Conclusion The MIC value for pathogens will help to determine the effective mode and form of probiotic that can be used for the treatment of peri-implantitis.