胃电图在功能性消化不良、关节过度活动和糖尿病性胃轻瘫患者中的应用。
Electrogastrography in Patients with Functional Dyspepsia, Joint Hypermobility, and Diabetic Gastroparesis.
机构信息
Department of Biomedical Engineering, İstanbul University, İstanbul, Turkey.
Department of Physiotherapy and Rehabilitation, İstanbul Bilim University, İstanbul, Turkey.
出版信息
Turk J Gastroenterol. 2022 Mar;33(3):182-189. doi: 10.5152/tjg.2021.20853.
BACKGROUND
Transcutaneous electrogastrography is a novel modality to assess the human stomach's gastric myoelectrical activity. The purpose of this study was to compare functional dyspepsia, joint hypermobility, and diabetic gastroparesis patients with healthy control subjects in terms of gastric motility abnormalities through electrogastrography evaluations, and to then evaluate the correlation among variations in their blood parameters.
METHODS
This study analyzed 120 subjects with functional dyspepsia (n = 30), joint hypermobility (n = 30), diabetic gastroparesis (n = 30), and control subjects (n = 30). The electrogastrography parameters included the dominant frequency, dominant power, power ratio, and instability coefficient, which were analyzed preprandially and postprandially. Although there are similar studies in the literature, there is no other study in which all groups have been studied together, as in our study.
RESULTS
The electrogastrography results showed that preprandial dominant frequency (P = .031*), dominant power (P = .047*), and instability coefficient (P = .043*), and postprandial dominant frequency (P = .041*) and dominant power (P = .035*) results were statistically significant among the functional dyspepsia, joint hypermobility, diabetic gastroparesis, and control groups. There was no significant difference found in terms of power ratio (P = .114) values. However, only glucose (P = .04*) and calcium (P = .04*) levels showed statistical significance. Several blood tests including hemoglobin (P = .032*), creatinine (P= .045*), calcium (P = .037*), potassium (P= .041*), white blood cells (P = .038*), and alanine aminotransferase (P = .031*) also showed correlation with the dominant frequency, power ratio, and instability coefficient parameters.
CONCLUSIONS
This joint methodology demonstrated that it is possible to differentiate between functional dyspepsia, joint hypermobility, and diabetic gastroparesis patients from healthy subjects by using electrogastrography. Moreover, the majority of patients showed adequate gastric motility in response to food.
背景
经皮胃电图是一种评估人体胃电活动的新方法。本研究的目的是通过胃电图评估，比较功能性消化不良、关节过度活动和糖尿病胃轻瘫患者与健康对照组之间的胃动力异常，并评估其血液参数变化之间的相关性。
方法
本研究分析了 120 名功能性消化不良患者（n=30）、关节过度活动患者（n=30）、糖尿病胃轻瘫患者（n=30）和对照组（n=30）。胃电图参数包括餐前和餐后的优势频率、优势功率、功率比和不稳定性系数。虽然文献中有类似的研究，但没有其他研究像我们的研究一样将所有组一起研究。
结果
胃电图结果显示，餐前优势频率（P=.031*）、优势功率（P=.047*）和不稳定性系数（P=.043*）以及餐后优势频率（P=.041*）和优势功率（P=.035*）在功能性消化不良、关节过度活动、糖尿病胃轻瘫和对照组之间具有统计学意义。功率比（P=.114）值没有显著差异。然而，只有血糖（P=.04*）和钙（P=.04*）水平具有统计学意义。包括血红蛋白（P=.032*）、肌酐（P=.045*）、钙（P=.037*）、钾（P=.041*）、白细胞（P=.038*）和丙氨酸氨基转移酶（P=.031*）在内的几项血液检查也与优势频率、功率比和不稳定性系数参数相关。
结论
这种联合方法表明，通过胃电图可以区分功能性消化不良、关节过度活动和糖尿病胃轻瘫患者与健康受试者。此外，大多数患者对食物有足够的胃动力反应。
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