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在研究股骨近端的生物力学研究中模拟关节软骨的一种原创方法。

An original method of simulating the articular cartilage in the context of biomechanical studies investigating the proximal femur.

作者信息

Gheorghevici Teodor Stefan, Carata Eugen, Sirbu Paul-Dan, Alexa Ovidiu, Poroh Manuela-Gabi, Filip Alexandru, Forna Norin, Puha Bogdan

机构信息

Department of Orthopedics and Traumatology, 'Sf. Spiridon' County Clinical Emergency Hospital, 700111 Iasi, Romania.

Department of Machine-Tools and Equipment of The Faculty of Machine Constructions and Industrial Management, 'Gheorghe Asachi' Technical University, 700050 Iasi, Romania.

出版信息

Exp Ther Med. 2022 Mar;23(3):202. doi: 10.3892/etm.2022.11125. Epub 2022 Jan 5.

DOI:10.3892/etm.2022.11125
PMID:35126705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8794553/
Abstract

Biomechanical testing is a necessity given the development of novel implants used in the osteosynthesis of hip fractures. The purpose of biomechanical testing is to recreate realistic conditions similar to the conditions. Although biomechanical testing of hip arthroplasty has been standardized since the 1970s, there is no consensus at present on testing methodology for osteosynthesis of hip fractures. Most biomechanical studies examining the fractures of the proximal femur in order to optimize implants opt for loading the bone-implant ensemble directly on the femoral head or using a metallic loading part. This loading technique fails to perform a mechanical stress distribution similar to conditions, which could alter the outcome. The present study aimed to design loading/unloading cups with mechanical properties that resemble those of the cartilage at the hip level. Through the impression and scanning of the cast models obtained, a digital 3D model was created in STL format and this was processed in order to obtain the computer numerical control (CNC) trajectories of the printing head. For prototyping using additive manufacturing technology, a thermoplastic polymer with biochemical properties, such as tensile strength, that resemble those of the adult hip and a Stratasys FORTUS 250 mc CNC machine were used. Loading/unloading cups with similar anatomy and biomechanical forces compared with those of the adult hip were created, which allowed the experimental simulation of the conditions during walking.

摘要

鉴于用于髋部骨折骨合成的新型植入物的发展,生物力学测试是必要的。生物力学测试的目的是重现与实际情况相似的逼真条件。尽管自20世纪70年代以来髋关节置换术的生物力学测试已经标准化,但目前对于髋部骨折骨合成的测试方法尚无共识。大多数为优化植入物而研究股骨近端骨折的生物力学研究选择直接在股骨头或使用金属加载部件对骨-植入物组合进行加载。这种加载技术无法实现与实际情况相似的机械应力分布,这可能会改变结果。本研究旨在设计具有与髋部软骨相似力学性能的加载/卸载杯。通过对获得的铸型模型进行印模和扫描,以STL格式创建了一个数字3D模型,并对其进行处理以获得打印头的计算机数控(CNC)轨迹。为了使用增材制造技术进行原型制作,使用了一种具有与成人髋部相似生化特性(如拉伸强度)的热塑性聚合物和一台Stratasys FORTUS 250 mc CNC机器。创建了与成人髋部具有相似解剖结构和生物力学力的加载/卸载杯,这使得能够对行走过程中的情况进行实验模拟。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/91e31fe416c8/etm-23-03-11125-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/eadd512c6b40/etm-23-03-11125-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/4fcb29432f56/etm-23-03-11125-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/1c0cc0a1726e/etm-23-03-11125-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/028d08a16e6e/etm-23-03-11125-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/4a7f24e26f2a/etm-23-03-11125-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/8c795da2344c/etm-23-03-11125-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/beeba5e140ce/etm-23-03-11125-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/91e31fe416c8/etm-23-03-11125-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/eadd512c6b40/etm-23-03-11125-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/4fcb29432f56/etm-23-03-11125-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/1c0cc0a1726e/etm-23-03-11125-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/028d08a16e6e/etm-23-03-11125-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/4a7f24e26f2a/etm-23-03-11125-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/8c795da2344c/etm-23-03-11125-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/beeba5e140ce/etm-23-03-11125-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb04/8794553/91e31fe416c8/etm-23-03-11125-g07.jpg

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