University of Central Florida/HCA Consortium, Tallahassee, FL, USA.
Dermatology Associates of Tallahassee, Tallahassee, FL, USA.
Skin Therapy Lett. 2024 Mar;29(2):1-6.
Hidradenitis suppurativa (HS) is a severe, debilitating, chronic inflammatory skin disease characterized by recurrent painful nodules, abscesses and draining sinus tracts in intertriginous areas. While this condition appears to stem from follicular unit dysfunction, its cause is multifactorial and the exact pathogenesis has yet to be fully elucidated. These factors make treatment selection challenging and contribute to variable therapeutic response among affected patients. Typical regimens consist of a combination of medical and surgical modalities, tailored to individual responses. However, HS is often refractory to traditional treatments, prompting the need for newer and more effective therapies. Herein, we review current and emerging HS therapies.
化脓性汗腺炎（HS）是一种严重的、使人虚弱的、慢性炎症性皮肤病，其特征是反复发作的疼痛性结节、脓肿和在皱褶部位有渗出窦道。虽然这种情况似乎源于毛囊单位功能障碍，但它的病因是多因素的，确切的发病机制尚未完全阐明。这些因素使得治疗选择具有挑战性，并导致受影响患者之间的治疗反应存在差异。典型的方案包括针对个体反应的医疗和手术方式的组合。然而，HS 通常对传统治疗方法有抗药性，因此需要新的、更有效的治疗方法。在此，我们综述了目前和新兴的 HS 治疗方法。
