Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Department of Behavioural Science and Health, Cancer Communication and Screening Group, University College London, London, UK.
Psychooncology. 2022 Jul;31(7):1110-1119. doi: 10.1002/pon.5897. Epub 2022 Feb 12.
To examine the impact of self-reported human papillomavirus (HPV) test result (HPV negative, HPV positive, HPV result unknown) on a range of psychosocial outcomes.
Women and other people with a cervix in Australia aged 25-74 years who reported having participated in cervical screening since December 2017 were recruited through Facebook and Instagram to complete an online survey. The primary outcome measures were anxiety, emotional distress, and general distress.
Nine hundred fifteen participants completed the online survey; 73.2% reported testing HPV negative ('HPV-'), 15% reported testing HPV positive ('HPV+') and 11.8% reported that they did not know/remember their test result ('HPV unknown'). Compared to participants testing HPV-, participants testing HPV+ had higher mean anxiety (41.67 vs. 37.08, p < 0.001) and emotional distress scores (11.88 vs. 7.71, p < 0.001). Concern about test result (34.3% vs. 1.3%, p < 0.001), perceived risk compared to average women (55.4% vs. 14.1%, p < 0.001), and cancer worry (27.8% vs. 5.9%, p < 0.001) were also greater among HPV+ participants than participants testing HPV-. Participants testing HPV+ felt less reassured about their screening result than participants testing HPV- (16% vs. 75.1%, p < 0.001). Participants testing HPV+ had greater knowledge of HPV (11.96 vs. 10.36 out of 16, p < 0.001) and HPV testing (3.94 vs 3.28 out of 5, p < 0.001) than participants who reported testing HPV-.
Elevated levels of anxiety and emotional distress were found in those testing HPV+ compared with those testing HPV-. Future research should examine what strategies should be used to deliver test results and what additional information is provided, in order to alleviate anxiety among individuals testing HPV+.
研究自我报告的人乳头瘤病毒（HPV）检测结果（HPV 阴性、HPV 阳性、HPV 结果未知）对一系列心理社会结局的影响。
招募澳大利亚年龄在 25-74 岁之间、自 2017 年 12 月以来有过宫颈筛查经历的女性和其他有宫颈的人群，通过 Facebook 和 Instagram 邀请他们完成在线调查。主要结局指标为焦虑、情绪困扰和一般困扰。
915 名参与者完成了在线调查；73.2%报告 HPV 检测结果为阴性（“HPV-”），15%报告 HPV 检测结果为阳性（“HPV+”），11.8%报告不知道/不记得自己的检测结果（“HPV 未知”）。与 HPV-组相比，HPV+组的参与者焦虑（41.67 比 37.08，p<0.001）和情绪困扰评分（11.88 比 7.71，p<0.001）更高。对检测结果的担忧（34.3%比 1.3%，p<0.001）、与一般女性相比的感知风险（55.4%比 14.1%，p<0.001）以及对癌症的担忧（27.8%比 5.9%，p<0.001）在 HPV+组也更高。与 HPV-组相比，HPV+组的参与者对筛查结果的信心更低（16%比 75.1%，p<0.001）。HPV+组参与者对 HPV（16 分中的 11.96 分比 10.36 分，p<0.001）和 HPV 检测（5 分中的 3.94 分比 3.28 分，p<0.001）的了解程度高于报告 HPV-的参与者。
与 HPV-组相比，HPV+组的焦虑和情绪困扰水平更高。未来的研究应该探讨应该使用哪些策略来提供检测结果以及提供哪些额外信息，以减轻 HPV 检测阳性个体的焦虑。
