Tehranian Afsaneh, Vahid Dastjerdi Marzieh, Hatamian Sare, Ghahghaei-Nezamabadi Akram
Department of Obstetrics and Gynecology, Arash Women's Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Family Reprod Health. 2024 Sep;18(3):154-159. doi: 10.18502/jfrh.v18i3.16656.
Considering the prevalence of Human Papillomavirus (HPV) infection and the lack of HPV vaccination program in Iran among young women and the importance of quality of life and sexual performance in women, we decided to conduct a study to examine the relationship between HPV infection and sexual dysfunction and quality of life in Iranian women.
In this cohort study, 250 married women who infected with HPV were recruited via convinence sampling from colposcopy clinic of Arash women hospital (Tehran, Iran) from April 2020 to May 2022.They were evaluated concerning their sexual function in the domains of desire, arousal, lubrication, orgasm, satisfaction and pain with the female sexual function index (FSFI) questionnaire (the total FSFI score is calculated by the sum of the nineteen items). Sexual quality of life-female (SQOL-F) items (Likert-type scale with a cut-off of 65 points) were organized into four sub-scales: psychosexual feelings, sexual and relationship satisfaction, self-worthlessness, and sexual repression. All patients filled out the female sexual function index (FSFI) and sexual quality of life (SQOL) questionnaires. Variables were analysed via correlation coefficient and linear regression tests.
Mean age and mean marriage duration were 38.5±4.5 and 12.2±7.2, respectively. There was a weak correlation between FSFI and SQOL (r=0.15, p=0.001).Time of marriage and genital warts were the predictors on the FSFI and SQOL.
The findings suggest that HPV infection can impair sexual function and quality of life. This research contributes valuable insights, especially considering the prevalence of HPV.
鉴于伊朗年轻女性中人类乳头瘤病毒（HPV）感染的普遍性以及该国缺乏HPV疫苗接种计划，同时考虑到女性生活质量和性功能的重要性，我们决定开展一项研究，以探讨伊朗女性HPV感染与性功能障碍及生活质量之间的关系。
在这项队列研究中，2020年4月至2022年5月期间，通过便利抽样从德黑兰阿拉什妇女医院的阴道镜检查诊所招募了250名感染HPV的已婚女性。使用女性性功能指数（FSFI）问卷评估她们在性欲、性唤起、润滑、性高潮、满意度和疼痛等方面的性功能（FSFI总分由19个项目的得分总和计算得出）。女性性生活质量（SQOL-F）项目（李克特量表，临界值为65分）分为四个子量表：性心理感受、性与关系满意度、自我无价值感和性压抑。所有患者均填写了女性性功能指数（FSFI）和性生活质量（SQOL）问卷。通过相关系数和线性回归检验对变量进行分析。
平均年龄和平均婚姻持续时间分别为38.5±4.5岁和12.2±7.2年。FSFI与SQOL之间存在弱相关性（r = 0.15，p = 0.001）。婚姻时长和尖锐湿疣是FSFI和SQOL的预测因素。
研究结果表明，HPV感染会损害性功能和生活质量。尤其是考虑到HPV的流行情况，本研究提供了有价值的见解。
