Sheshadri Ajay, Makhnoon Sukh, Alousi Amin M, Bashoura Lara, Andrade Rene, Miller Christopher J, Stolar Karen R, Arain Muhammad Hasan, Noor Laila, Balagani Amulya, Jain Akash, Blanco David, Ortiz Abel, Taylor Michael S, Stenzler Alex, Mehta Rohtesh, Popat Uday R, Hosing Chitra, Ost David E, Champlin Richard E, Dickey Burton F, Peterson Susan K
Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Department of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
JMIR Form Res. 2022 Feb 7;6(2):e29393. doi: 10.2196/29393.
Home-based spirometry (HS) allows for the early detection of lung complications in recipients of an allogeneic hematopoietic cell transplant (AHCT). Although the usability and acceptability of HS are critical for adherence, patient-reported outcomes of HS use remain poorly understood in this setting.
The aim of this study is to design a longitudinal, mixed methods study to understand the usability and acceptability of HS among recipients of AHCT.
Study participants performed HS using a Bluetooth-capable spirometer that transmitted spirometry data to the study team in real time. In addition, participants completed usability questionnaires and in-depth interviews and reported their experiences with HS. Analysis of interview data was guided by the constructs of performance expectancy, effort expectancy, and social influence from the Unified Theory of Acceptance and Use of Technology model.
Recipients of AHCT found HS to be highly acceptable despite modest technological barriers. On average, participants believed that the HS was helpful in managing symptoms related to AHCT (scores ranging from 2.22 to 2.68 on a scale of 0-4) and for early detection of health-related problems (score range: 2.88-3.12). Participants viewed HS favorably and were generally supportive of continued use. No significant barriers to implementation were identified from the patient's perspective. Age and gender were not associated with the patient perception of HS.
Study participants found HS acceptable and easy to use. Some modifiable technical barriers to performing HS were identified; however, wider implementation of pulmonary screening is feasible from the patient's perspective.
家庭肺功能测定（HS）有助于早期发现异基因造血细胞移植（AHCT）受者的肺部并发症。尽管HS的可用性和可接受性对依从性至关重要，但在这种情况下，患者报告的HS使用结果仍知之甚少。
本研究旨在设计一项纵向混合方法研究，以了解AHCT受者对HS的可用性和可接受性。
研究参与者使用具有蓝牙功能的肺活量计进行HS，该肺活量计可将肺功能测定数据实时传输给研究团队。此外，参与者完成了可用性问卷和深入访谈，并报告了他们使用HS的经历。访谈数据分析以技术接受与使用统一理论模型中的绩效期望、努力期望和社会影响结构为指导。
尽管存在一些适度的技术障碍，但AHCT受者发现HS非常可接受。平均而言，参与者认为HS有助于管理与AHCT相关的症状（在0-4分的量表上得分范围为2.22至2.68）以及早期发现与健康相关的问题（得分范围：2.88-3.12）。参与者对HS评价良好，普遍支持继续使用。从患者的角度来看，未发现实施的重大障碍。年龄和性别与患者对HS的认知无关。
研究参与者发现HS是可接受且易于使用的。确定了一些进行HS的可修改技术障碍；然而，从患者的角度来看，更广泛地实施肺部筛查是可行的。
