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猪脑在水平面的多区域黏弹性特性。

Multiregional viscoelastic properties of the porcine brain in the horizontal plane.

机构信息

School of Mechanical Engineering, Shandong University, Jinan, 250061, China.

Key Laboratory of High Efficiency and Clean Mechanical Manufacture (Shandong University), Ministry of Education, Jinan, 250061, China.

出版信息

Med Biol Eng Comput. 2022 Mar;60(3):855-862. doi: 10.1007/s11517-022-02517-z. Epub 2022 Feb 7.

DOI:10.1007/s11517-022-02517-z
PMID:35129764
Abstract

Comparison between the corpus callosum and different regions of corona radiata in the horizontal plane was tested in the article. A series of flat-punch indentation experiments were conducted on the corpus callosum and different regions of corona radiata with different loading rates on the porcine brain. A linear viscoelastic model with prony series approximation was fitted to the force-time data of all regions. The experiment data from different loading rates demonstrated that both the corona radiata and corpus callosum increased in stiffness with the increasing loading rates. The corona radiata seems to be stiffer than the corpus callosum in the horizontal plane. During the period of relaxation, statistical comparisons among the different regions showed that the posterior region of the corona radiata seems to be stiffer than the anterior and superior.

摘要

本文比较了大脑水平切面上胼胝体与冠状辐射区不同部位的力学性能。对猪脑进行了一系列不同加载速率的平面冲头压痕实验,对胼胝体和冠状辐射区的不同部位进行了实验。使用 Prony 级数逼近拟合了所有区域的力-时间数据。不同加载速率的实验数据表明,冠状辐射区和胼胝体的刚度都随加载速率的增加而增加。冠状辐射区在水平面上似乎比胼胝体更硬。在松弛阶段,对不同区域的统计比较表明,冠状辐射区的后区似乎比前区和上区更硬。

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本文引用的文献

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Towards a reliable characterisation of the mechanical behaviour of brain tissue: The effects of post-mortem time and sample preparation.迈向对脑组织力学行为的可靠表征:死后时间和样本制备的影响。
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Shear Properties of Brain Tissue over a Frequency Range Relevant for Automotive Impact Situations: New Experimental Results.汽车碰撞情况下相关频率范围内脑组织的剪切特性:新的实验结果。
Stapp Car Crash J. 2004 Nov;48:239-58. doi: 10.4271/2004-22-0011.
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The high frequency properties of brain tissue.脑组织的高频特性。
Biorheology. 2004;41(6):681-91.