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腹腔镜带环吻合胃旁路术:单中心系列研究。

Laparoscopic Banded One Anastomosis Gastric Bypass: A Single-Center Series.

机构信息

Department of Bariatric and Metabolic Surgery, San Carlo of Nancy Hospital and University of Rome "Tor Vergata", Rome, Italy.

Chair of Psychiatry, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

出版信息

J Obes. 2022 Jan 29;2022:4942052. doi: 10.1155/2022/4942052. eCollection 2022.

DOI:10.1155/2022/4942052
PMID:35132363
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8817855/
Abstract

INTRODUCTION

Laparoscopic one anastomosis gastric bypass (LOAGB) is a relatively new procedure for the treatment of morbid obesity and related comorbidities. On average, this procedure results in good postoperative weight loss with a low complication rate. Recent publications suggest that dumping syndrome and weight regain might be reduced by placing a silicone ring over the gastric pouch during the procedure, so called laparoscopic banded one anastomosis gastric bypass (LBOAGB).

METHODS

86 patients undergoing LBOAGB between 2018 and 2020 were enrolled in this retrospective study. Hospital records were used to assess weight loss, comorbidity resolution, and any complications either in the short or medium term.

RESULTS

54 Female and 32 male patients were included with a mean age of 43 years (25-64), preoperative body mass index of 42 kg/m (35-49), and preoperative weight of 114 kg (86-162). Thirty-four patients presented with type 2 diabetes (39.5%), 42 patients (49%) diagnosed with hypertension, 24 presented with OSAS (28%), and 21 (24%) hypercholesterolaemia patients were included. In total, 36 patients were diagnosed with multiple comorbidities. The operative data showed an average operative time of 48 minutes with 3.4% of patients suffering from early (minor) complications and 2.3% with a late (minor) complication. One patient required reoperation due to intra-abdominal bleeding. The median length of hospital stay was 2.5 days. Median follow-up was 18 months (5-36). In that period, no patient required ring removal or conversion to Roux-en-Y gastric bypass surgery. Food intolerance/vomiting was present in 1 patient (1.1%), bile reflux was present in 1 patient (1.1%), and no stomal ulcers were observed. Mean % excess weight loss at 12 and 24 months was 72% and 80%, respectively. Fifty-two out of 86 patients (60%) had a complete resolution of comorbidities. A CONUT score >2 (mild malnutrition) was found in 40% of patients, while a CONUT score 0-1 was found in 60% of patients.

CONCLUSION

LBOAGB shows promising results in terms of safety and efficacy in the short term. Further prospective studies will be required to evaluate the consistency of the results in the long term.

摘要

介绍

腹腔镜单吻合口胃旁路术(LOAGB)是一种治疗病态肥胖及其相关合并症的相对较新的手术方法。平均而言,该手术可实现良好的术后减重效果,且并发症发生率较低。最近的出版物表明,在手术过程中在胃袋上放置硅酮环可能会减少倾倒综合征和体重反弹,因此称为腹腔镜带吻合口胃旁路术(LBOAGB)。

方法

本回顾性研究纳入了 2018 年至 2020 年间接受 LBOAGB 的 86 例患者。使用医院记录评估短期和中期的体重减轻、合并症缓解和任何并发症。

结果

54 名女性和 32 名男性患者入组,平均年龄为 43 岁(25-64 岁),术前体重指数为 42kg/m²(35-49),术前体重为 114kg(86-162kg)。34 例患者患有 2 型糖尿病(39.5%),42 例(49%)患者诊断为高血压,24 例患者出现阻塞性睡眠呼吸暂停低通气综合征(28%),21 例(24%)高胆固醇血症患者。总共 36 例患者被诊断为多种合并症。手术数据显示平均手术时间为 48 分钟,3.4%的患者发生早期(轻微)并发症,2.3%的患者发生晚期(轻微)并发症。1 例患者因腹腔内出血需要再次手术。中位住院时间为 2.5 天。中位随访时间为 18 个月(5-36 个月)。在此期间,没有患者需要取出戒指或转为 Roux-en-Y 胃旁路手术。1 例(1.1%)患者出现食物不耐受/呕吐,1 例(1.1%)患者出现胆汁反流,未观察到吻合口溃疡。术后 12 个月和 24 个月的平均体重减轻率分别为 72%和 80%。86 例患者中有 52 例(60%)完全缓解了合并症。40%的患者 CONUT 评分>2(轻度营养不良),60%的患者 CONUT 评分 0-1。

结论

LBOAGB 在短期的安全性和有效性方面显示出良好的结果。需要进一步的前瞻性研究来评估长期结果的一致性。

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