Novick Andrew M, Johnson Rachel L, Lazorwitz Aaron, Belyavskaya Anna, Berkowitz Lily, Norton Aileen, Sammel Mary D, Epperson C Neill
Department of Psychiatry, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA.
Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA.
Eur J Contracept Reprod Health Care. 2022 Jun;27(3):212-220. doi: 10.1080/13625187.2022.2030702. Epub 2022 Feb 8.
To evaluate if adverse childhood experiences are associated with hormonal contraception discontinuation due to mood and sexual side effects.
Women, ages 18-40 ( = 826), with current and/or previous hormonal contraceptive use completed surveys on demographics, contraceptive history, and the Adverse Childhood Experiences Questionnaire. We characterised women into high (≥2 adverse experiences) and low (0 or 1) adverse childhood experience groups. We calculated risk ratios for associations between adverse childhood experiences and outcomes of interest using log binomial generalised linear models, and adjusted for relevant demographic variables.
Women in the high adverse childhood experiences group ( = 355) were more likely to report having discontinued hormonal contraception due to decreases in sexual desire (adjusted risk ratio 1.44, 1.03-2.00, = .030). Covariates included age, current hormonal contraception use, and various demographic variables associated with discontinuation. Adverse childhood experiences were not associated with mood or sexual side effects among current ( = 541) hormonal contraceptive users.
Self-reported adverse childhood experiences were associated with greater likelihood of discontinuing hormonal contraception due to behavioural side effects, particularly decreases in sexual desire. Identification of risk factors for behavioural side effects can assist patients and clinicians in making informed choices on contraception that minimise risk of early discontinuation.
评估童年不良经历是否与因情绪和性方面的副作用而停用激素避孕法有关。
年龄在18 - 40岁（n = 826）、目前正在使用和/或曾经使用过激素避孕法的女性完成了关于人口统计学、避孕史和童年不良经历问卷的调查。我们将女性分为童年不良经历高（≥2次不良经历）和低（0次或1次）两组。我们使用对数二项式广义线性模型计算童年不良经历与感兴趣的结果之间关联的风险比，并对相关人口统计学变量进行了调整。
童年不良经历高分组（n = 355）的女性更有可能报告因性欲下降而停用激素避孕法（调整后的风险比为1.44，95%置信区间为1.03 - 2.00，P = 0.030）。协变量包括年龄、当前激素避孕法的使用情况以及与停用相关的各种人口统计学变量。童年不良经历与目前正在使用激素避孕法的女性（n = 541）的情绪或性方面的副作用无关。
自我报告的童年不良经历与因行为副作用（尤其是性欲下降）而停用激素避孕法的可能性增加有关。识别行为副作用的风险因素可以帮助患者和临床医生在避孕方面做出明智的选择，将早期停用的风险降至最低。
