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Benign adenomyoepitelioma of the breast: Presentation of two rare cases and review of literature.乳腺良性腺肌上皮瘤:两例罕见病例报告及文献复习
Int J Surg Case Rep. 2020;67:1-4. doi: 10.1016/j.ijscr.2020.01.010. Epub 2020 Jan 23.
3
Clinical presentation, national practice patterns, and outcomes of breast adenomyoepithelioma.乳腺腺肌上皮瘤的临床表现、国家实践模式和结局。
Breast J. 2020 Apr;26(4):653-660. doi: 10.1111/tbj.13638. Epub 2019 Oct 2.
4
Radiotherapy in the Multidisciplinary Management of Adenomyoepithelioma of the Breast with an Axillary Lymph Node Metastasis: A Case Report and Review of the Literature.伴有腋窝淋巴结转移的乳腺腺肌上皮瘤多学科管理中的放射治疗:一例报告及文献复习
Cureus. 2017 Jun 21;9(6):e1380. doi: 10.7759/cureus.1380.
5
Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: A case series emphasizing histologic, radiologic, and clinical correlation.乳腺腺肌上皮瘤及伴癌的腺肌上皮瘤(恶性腺肌上皮瘤)与相关乳腺恶性肿瘤:一项强调组织学、放射学及临床相关性的病例系列研究。
Breast. 2016 Oct;29:132-9. doi: 10.1016/j.breast.2016.07.018. Epub 2016 Aug 3.
6
The mammography and MRI manifestations of adenomyoepithelioma of the breast.乳腺腺肌上皮瘤的乳腺钼靶和磁共振成像表现。
Clin Radiol. 2016 Mar;71(3):235-43. doi: 10.1016/j.crad.2015.11.005. Epub 2015 Dec 22.
7
Breast adenomyoepithelioma: a case report with malignant proliferation of epithelial and myoepithelial elements.乳腺腺肌上皮瘤:上皮和肌上皮成分恶性增殖的 1 例报告。
World J Surg Oncol. 2013 Oct 30;11:285. doi: 10.1186/1477-7819-11-285.
8
Bilateral adenomyoepithelioma of breast.双侧乳腺腺肌上皮瘤
J Cancer Res Ther. 2013 Jul-Sep;9(3):523-5. doi: 10.4103/0973-1482.119370.
9
Malignant transformation of adenomyoepithelioma of the breast by a monophasic population: a report of two cases and review of literature.乳腺腺肌上皮瘤的单相型恶变:两例报告及文献复习。
APMIS. 2013 Apr;121(4):272-9. doi: 10.1111/j.1600-0463.2012.02982.x. Epub 2012 Sep 13.
10
Adenomyoepithelial tumors of the breast: imaging findings with histopathologic correlation.乳腺腺肌上皮瘤:与组织病理学相关性的影像学表现。
AJR Am J Roentgenol. 2011 Jul;197(1):W184-90. doi: 10.2214/AJR.10.6064.

乳腺腺肌上皮瘤:一种罕见的诊断,因手术紧急情况和诊断不确定性而变得复杂。

Adenomyoepithelioma of the breast: a rare diagnosis complicated by surgical emergency and diagnostic uncertainty.

机构信息

Academic Centre, Milton Keynes University Hospital, Milton Keynes, UK

Academic Centre, Milton Keynes University Hospital, Milton Keynes, UK.

出版信息

BMJ Case Rep. 2022 Feb 8;15(2):e246390. doi: 10.1136/bcr-2021-246390.

DOI:10.1136/bcr-2021-246390
PMID:35135791
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8830098/
Abstract

A woman in her 80s was referred as an emergency case with a large oedematous and ulcerating lesion of the right breast. There was a 5-month history of increasing breast volume with new onset skin breakdown and discharge. Imaging revealed an extensive heterogeneous mass requiring drainage. No diagnosis was received from multiple biopsies and immediate surgical resection of the breast and axillary sampling was prioritised given the deteriorating patient condition. Postoperative histology identified a biphasic Adenomyoepithelioma of low malignant potential, a rare presentation compounding the complexity of management. The diagnostic uncertainty of this case highlighted the importance of MDT collaboration and the flexibility of current management pathways when dealing with cases requiring urgent surgical intervention. Axillary sampling in the context of unsuccessful preoperative biopsy represented a comprehensive means for assessing the need for further surgical or systemic management in the context of unconfirmed malignancy in a deteriorating patient.

摘要

一位 80 多岁的女性因右乳房出现大面积水肿性溃疡病变而被紧急转介。她的乳房体积在过去 5 个月逐渐增大,新出现皮肤破裂和分泌物。影像学检查显示广泛的异质性肿块,需要引流。多次活检均未得出明确诊断,鉴于患者病情恶化,应优先进行乳房和腋窝取样的立即手术切除。术后组织学检查确定为低度恶性潜能的双相型腺肌上皮瘤,这种罕见的表现使治疗变得更加复杂。该病例的诊断不确定性突出了多学科团队合作的重要性,以及在处理需要紧急手术干预的病例时,当前管理途径的灵活性。在术前活检未成功的情况下进行腋窝取样,代表了在病情恶化的疑似恶性肿瘤患者中,为进一步手术或系统治疗提供全面评估的手段。