Academic Centre, Milton Keynes University Hospital, Milton Keynes, UK
Academic Centre, Milton Keynes University Hospital, Milton Keynes, UK.
BMJ Case Rep. 2022 Feb 8;15(2):e246390. doi: 10.1136/bcr-2021-246390.
A woman in her 80s was referred as an emergency case with a large oedematous and ulcerating lesion of the right breast. There was a 5-month history of increasing breast volume with new onset skin breakdown and discharge. Imaging revealed an extensive heterogeneous mass requiring drainage. No diagnosis was received from multiple biopsies and immediate surgical resection of the breast and axillary sampling was prioritised given the deteriorating patient condition. Postoperative histology identified a biphasic Adenomyoepithelioma of low malignant potential, a rare presentation compounding the complexity of management. The diagnostic uncertainty of this case highlighted the importance of MDT collaboration and the flexibility of current management pathways when dealing with cases requiring urgent surgical intervention. Axillary sampling in the context of unsuccessful preoperative biopsy represented a comprehensive means for assessing the need for further surgical or systemic management in the context of unconfirmed malignancy in a deteriorating patient.
一位 80 多岁的女性因右乳房出现大面积水肿性溃疡病变而被紧急转介。她的乳房体积在过去 5 个月逐渐增大,新出现皮肤破裂和分泌物。影像学检查显示广泛的异质性肿块,需要引流。多次活检均未得出明确诊断,鉴于患者病情恶化,应优先进行乳房和腋窝取样的立即手术切除。术后组织学检查确定为低度恶性潜能的双相型腺肌上皮瘤,这种罕见的表现使治疗变得更加复杂。该病例的诊断不确定性突出了多学科团队合作的重要性,以及在处理需要紧急手术干预的病例时,当前管理途径的灵活性。在术前活检未成功的情况下进行腋窝取样,代表了在病情恶化的疑似恶性肿瘤患者中,为进一步手术或系统治疗提供全面评估的手段。