Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Department of Physical Therapy, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Comput Math Methods Med. 2022 Jan 30;2022:3059629. doi: 10.1155/2022/3059629. eCollection 2022.
Diabetes mellitus type 2 and vitamin D deficiency are both prevalent in the Saudi Arabia. Vitamin D deficiency treatment with supplements carries a risk of intoxication.
The present study is aimed at elucidating the effect of exercise on modulation of metabolic status and vitamin D level in patients with type 2 diabetes mellitus (T2DM).
A sum of 110 type 2 diabetic patients were voluntarily enrolled for the present investigation by dividing them into two separate groups (55 individuals for each group), the diabetic study group and diabetic control group. The diabetic study group was engaged in the training program using treadmill exercise. Laboratory parameters were monitored before and after the training program.
There were significant elevation in the diabetic study group compared to diabetic control group regarding postexercise vitamin D level, high-density lipoprotein (HDL) ( value ≤ 0.001, 0.045; respectively). In addition, triglycerides, low-density lipoprotein (LDL), glycosylated hemoglobin (HbA1C), and homeostatic model assessment-insulin resistance (HOMA-IR) were significantly decreased ( value < 0.001 for all mentioned parameters). Moreover, there were significant higher level in postexercise parameters as compared to preexercise level in the diabetic study group.
The exercise training program improved the metabolic control and vitamin D level after three months of intervention.
2 型糖尿病和维生素 D 缺乏在沙特阿拉伯都很普遍。维生素 D 缺乏症的补充治疗有中毒的风险。
本研究旨在阐明运动对 2 型糖尿病（T2DM）患者代谢状态和维生素 D 水平的调节作用。
共有 110 名 2 型糖尿病患者自愿参加了本研究，将他们分为两组（每组 55 人），即糖尿病研究组和糖尿病对照组。糖尿病研究组采用跑步机运动进行训练计划。在训练计划前后监测实验室参数。
与糖尿病对照组相比，糖尿病研究组运动后维生素 D 水平、高密度脂蛋白（HDL）（ 值≤0.001，0.045）显著升高。此外，甘油三酯、低密度脂蛋白（LDL）、糖化血红蛋白（HbA1C）和稳态模型评估-胰岛素抵抗（HOMA-IR）显著降低（所有提到的参数 值均<0.001）。此外，与运动前相比，糖尿病研究组运动后的参数水平显著升高。
运动训练计划在干预三个月后改善了代谢控制和维生素 D 水平。
