Department of Nutrition and Dietetics, Avantmèdic, 25008, Lleida, Spain.
Department of Endocrinology and Nutrition, Health Sciences Research Institute Germans Trias i Pujol, 08916, Badalona, Spain.
Health Qual Life Outcomes. 2018 Mar 12;16(1):44. doi: 10.1186/s12955-018-0873-3.
In this cross-sectional study, we assessed the possible association of vitamin D deficiency with self-reported treatment satisfaction and health-related quality of life in patients with type 2 diabetes.
We performed a sub-analysis of a previous study and included a total of 292 type 2 diabetic patients. We evaluated treatment satisfaction and health-related quality of life through specific tools: the Diabetes Treatment Satisfaction Questionnaire and the Audit of Diabetes-Dependent Quality of Life. Vitamin D deficiency was defined as 25 (OH) D serum levels < 15 ng/mL.
Multivariable linear regression models were used to estimate the relationship of vitamin D deficiency with both outcomes once adjusted for self-reported patient characteristics. Vitamin D deficiency was significantly associated with the final score of the Diabetes Treatment Satisfaction Questionnaire and the single "diabetes-specific quality of life" dimension of the Audit of Diabetes-Dependent Quality of Life (p = 0.0198 and p = 0.0070, respectively). However, lower concentrations of 25-OH vitamin D were not associated with the overall quality of life score or the perceived frequency of hyperglycaemia and hypoglycaemia.
Our study shows the association between vitamin D deficiency and both the self-reported diabetes treatment satisfaction and the diabetes-specific quality of life in patients with type 2 diabetes.
在这项横断面研究中，我们评估了维生素 D 缺乏与 2 型糖尿病患者报告的治疗满意度和健康相关生活质量之间可能存在的关联。
我们对先前的一项研究进行了亚分析，共纳入 292 例 2 型糖尿病患者。我们通过特定的工具评估治疗满意度和健康相关的生活质量：糖尿病治疗满意度问卷和糖尿病相关生活质量评估。维生素 D 缺乏定义为 25（OH）D 血清水平<15ng/mL。
多变量线性回归模型用于估计维生素 D 缺乏与这两个结果之间的关系，在调整了自我报告的患者特征后。维生素 D 缺乏与糖尿病治疗满意度问卷的最终评分和糖尿病相关生活质量评估的单一“糖尿病特异性生活质量”维度显著相关（p=0.0198 和 p=0.0070，分别）。然而，25-OH 维生素 D 浓度较低与整体生活质量评分或高血糖和低血糖的感知频率无关。
我们的研究表明，维生素 D 缺乏与 2 型糖尿病患者报告的糖尿病治疗满意度和糖尿病特异性生活质量之间存在关联。
