Watashi Diego M, Sene Diogo R, Garófalo Júlia B, Merlini Renan H, Merlini Alexandre B
Internal Medicine, Universidade de Mogi das Cruzes, Mogi das Cruzes, BRA.
Intensive Care Unit, Hospital Dr. Arnaldo Pezzuti Cavalcanti, Mogi das Cruzes, BRA.
Cureus. 2021 Dec 29;13(12):e20806. doi: 10.7759/cureus.20806. eCollection 2021 Dec.
During the SARS-CoV-2 pandemic, various rashes associated with COVID-19 infection have been reported, including urticaria. Urticaria is a limited and usually benign condition, presenting as pruritic wheals, with or without edema. A 39-year-old woman presented with a pruritic rash on her arms spreading to her trunk and face over two days, followed by headache, nausea, vomiting, abdominal discomfort, diarrhea, myalgia, arthralgia, anosmia, and dyspepsia for three days. Fever, dry cough, and odynophagia started on the day of the consult. The patient had a history of hypertension but denied a history of atopic conditions, similar previous presentations, or recent ingestion of new medications. SARS-CoV-2 COVID-19 PCR testing was positive. She was prescribed oral antihistamine for the itching and was discharged. During a follow-up after two weeks, the patient was asymptomatic with complete resolution of the rash on day 7 of symptoms. Knowing the cutaneous manifestations of COVID-19 can aid in the early identification of this disease and prevent misdiagnosis. The presence of cutaneous manifestations in COVID-19 is suggested to be related to disease severity, but data are needed to study any prognostic value of dermatologic manifestations in COVID-19.
在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行期间，已有多种与新型冠状病毒肺炎（COVID-19）感染相关的皮疹报道，包括荨麻疹。荨麻疹是一种局限性且通常为良性的病症，表现为瘙痒性风团，可伴有或不伴有水肿。一名39岁女性在两天内双臂出现瘙痒性皮疹，并蔓延至躯干和面部，随后三天出现头痛、恶心、呕吐、腹部不适、腹泻、肌痛、关节痛、嗅觉丧失和消化不良。在就诊当天开始出现发热、干咳和吞咽疼痛。该患者有高血压病史，但否认有特应性疾病史、类似既往表现或近期服用新药史。SARS-CoV-2 COVID-19聚合酶链反应（PCR）检测呈阳性。她因瘙痒被开具口服抗组胺药后出院。在两周后的随访中，患者无症状，皮疹在症状出现第7天时完全消退。了解COVID-19的皮肤表现有助于早期识别该病并防止误诊。COVID-19中皮肤表现的出现被认为与疾病严重程度有关，但需要数据来研究皮肤病学表现在COVID-19中的任何预后价值。
