疟原虫的培养

Cultivation of malarial parasites.

作者信息

Trager W, Jenson J B

出版信息

Nature. 1978 Jun 22;273(5664):621-2. doi: 10.1038/273621a0.

Abstract

The method for continuous cultivation of Plasmodium falciparum has now been successfully applied to several strains from different geographical areas. It has been used for tests of antimalarial drugs, for studies of parasite-host cell interactions with special reference to sickle haemoglobin, and for the production of amounts of parasite sufficient for experimental immunisation of Aotus trivirgatus monkeys.

摘要

恶性疟原虫的连续培养方法现已成功应用于来自不同地理区域的多个菌株。它已被用于抗疟药物的测试、寄生虫与宿主细胞相互作用的研究（特别是针对镰状血红蛋白），以及生产足够数量的寄生虫用于对三带犰狳猴进行实验性免疫。