Vig Khushdeep S, Amarante Matthew, Hutchinson Ian, Lawrence James Patrick
Division of Orthopaedic Surgery, Albany Medical Center, Albany, NY 12208, United States.
N Am Spine Soc J. 2021 May 8;6:100067. doi: 10.1016/j.xnsj.2021.100067. eCollection 2021 Jun.
Spinal epidural abscess (SEA) in children is a rare condition with dangerous sequelae, and with only 22 other cases reported in the literature, treatment algorithms are poorly understood. Quick identification of the classic tried of sepsis, back pain and neurological deficit is critical. Source identification difficult and often cannot be identified. Reported pathogens include varicella-zoster virus, S. aureus, and S pyogenes.
We report a case of spontaneous pediatric SEA in a 22-month old female without obvious neurologic deficit, who underwent a T10-11 decompressive laminotomy and evacuation of abscess and subsequent 3-week course of intravenous ceftriaxone for culture positive S. pyogenes.
The patient showed marked improvement in symptoms after decompression. 5 weeks postoperatively after transitioning from intravenous ceftriaxone to oral ceftin, the patient redeveloped a deep space infection and was taken back for a repeat debridement. The cultures from this procedure were negative and the patient was discharged on oral clindamycin.
Pediatric spontaneous SEA is a rare condition and early diagnosis and surgical intervention if indicated can prevent dangerous sequelae. Further studies into the surgical indications for decompression will aid in algorithmic decision making.
儿童脊髓硬膜外脓肿(SEA)是一种罕见疾病,具有危险的后遗症,且文献中仅报道了22例其他病例,对其治疗方案了解甚少。快速识别败血症、背痛和神经功能缺损的典型表现至关重要。感染源难以确定,且往往无法查明。报道的病原体包括水痘-带状疱疹病毒、金黄色葡萄球菌和化脓性链球菌。
我们报告一例22个月大的自发性儿童SEA病例,该女童无明显神经功能缺损,接受了T10 - 11减压椎板切除术及脓肿清除术,随后因培养出化脓性链球菌阳性接受了为期3周的静脉注射头孢曲松治疗。
减压后患者症状明显改善。从静脉注射头孢曲松转为口服头孢呋辛酯5周后,患者再次发生深部感染,遂再次接受清创手术。此次手术培养结果为阴性,患者出院时口服克林霉素。
儿童自发性SEA是一种罕见疾病,早期诊断并在必要时进行手术干预可预防危险的后遗症。进一步研究减压的手术指征将有助于制定治疗方案。