Department of Physical Therapy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Shirley Ryan AbilityLab and Department of Physiology, Northwestern University, Hines VA Medical Center, Chicago, Illinois, USA.
Dev Med Child Neurol. 2022 Jun;64(6):700-708. doi: 10.1111/dmcn.15173. Epub 2022 Feb 10.
Skeletal muscles are required for functional movement and force production. While it is clear that cerebral palsy (CP) results in loss of muscle strength and bodily function, and that much of this loss is caused by injury to the central nervous system, muscle is a very plastic tissue that is also dramatically affected. In many studies, it is assumed that voluntary exercise will cause the muscle to respond in the same way that typically developing muscle does, but there are scarce data demonstrating that this is true. The purpose of this review is to briefly describe muscle architectural adaptation to various forms of exercise with specific reference to voluntary exercise performed in children with CP. Exercise itself is not generic but can vary by intensity, duration, and the exact nature of the muscle length change and velocity imposed during the exercise. Our goal is to stimulate discussion in this area by pointing out salient experimental variables and, ultimately, to improve activity and participation in children with CP.
骨骼肌是实现功能运动和力量产生的基础。脑瘫(CP)会导致肌肉力量和身体功能丧失,这一点非常明确,而这种丧失在很大程度上是由于中枢神经系统损伤所致,但肌肉是一种非常具有可塑性的组织,也会受到显著影响。在许多研究中,人们假设自愿运动将使肌肉以与正常发育肌肉相同的方式做出反应,但很少有数据表明这是正确的。本综述的目的是简要描述肌肉结构对各种形式运动的适应,特别是针对 CP 患儿进行的自愿运动。运动本身并不是通用的,而是可以根据强度、持续时间以及运动过程中肌肉长度变化和速度的具体性质而有所不同。我们的目标是通过指出明显的实验变量来激发该领域的讨论,并最终改善 CP 患儿的活动和参与度。