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自愿运动对脑瘫患者肌肉结构和功能的影响。

Effects of voluntary exercise on muscle structure and function in cerebral palsy.

机构信息

Department of Physical Therapy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.

Shirley Ryan AbilityLab and Department of Physiology, Northwestern University, Hines VA Medical Center, Chicago, Illinois, USA.

出版信息

Dev Med Child Neurol. 2022 Jun;64(6):700-708. doi: 10.1111/dmcn.15173. Epub 2022 Feb 10.

DOI:10.1111/dmcn.15173
PMID:35142371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9086177/
Abstract

Skeletal muscles are required for functional movement and force production. While it is clear that cerebral palsy (CP) results in loss of muscle strength and bodily function, and that much of this loss is caused by injury to the central nervous system, muscle is a very plastic tissue that is also dramatically affected. In many studies, it is assumed that voluntary exercise will cause the muscle to respond in the same way that typically developing muscle does, but there are scarce data demonstrating that this is true. The purpose of this review is to briefly describe muscle architectural adaptation to various forms of exercise with specific reference to voluntary exercise performed in children with CP. Exercise itself is not generic but can vary by intensity, duration, and the exact nature of the muscle length change and velocity imposed during the exercise. Our goal is to stimulate discussion in this area by pointing out salient experimental variables and, ultimately, to improve activity and participation in children with CP.

摘要

骨骼肌是实现功能运动和力量产生的基础。脑瘫(CP)会导致肌肉力量和身体功能丧失,这一点非常明确,而这种丧失在很大程度上是由于中枢神经系统损伤所致,但肌肉是一种非常具有可塑性的组织,也会受到显著影响。在许多研究中,人们假设自愿运动将使肌肉以与正常发育肌肉相同的方式做出反应,但很少有数据表明这是正确的。本综述的目的是简要描述肌肉结构对各种形式运动的适应,特别是针对 CP 患儿进行的自愿运动。运动本身并不是通用的,而是可以根据强度、持续时间以及运动过程中肌肉长度变化和速度的具体性质而有所不同。我们的目标是通过指出明显的实验变量来激发该领域的讨论,并最终改善 CP 患儿的活动和参与度。

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Differential DNA methylation and transcriptional signatures characterize impairment of muscle stem cells in pediatric human muscle contractures after brain injury.差异 DNA 甲基化和转录特征表明,脑损伤后小儿肌肉挛缩的肌肉干细胞受损。
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Resistance Training Combined With Stretching Increases Tendon Stiffness and Is More Effective Than Stretching Alone in Children With Cerebral Palsy: A Randomized Controlled Trial.
Narrative Review of the Theoretical-Methodological Foundations of the TREINI Program.
TREINI计划理论方法基础的叙述性综述
Children (Basel). 2024 Sep 27;11(10):1181. doi: 10.3390/children11101181.
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Motor practice related changes in the sensorimotor cortices of youth with cerebral palsy.脑瘫青少年感觉运动皮层中与运动练习相关的变化。
Brain Commun. 2024 Sep 26;6(5):fcae332. doi: 10.1093/braincomms/fcae332. eCollection 2024.
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Alpha oscillations during visual selective attention are aberrant in youth and adults with cerebral palsy.在患有脑瘫的青少年和成年人中,视觉选择性注意期间的 alpha 振荡是异常的。
Cereb Cortex. 2024 Sep 3;34(9). doi: 10.1093/cercor/bhae365.
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Effects of progressive functional ankle exercises in spastic cerebral palsy, plantarflexors versus dorsiflexors: a randomized trial.痉挛性脑瘫中渐进性功能性踝关节运动对跖屈肌和背屈肌的影响:一项随机试验。
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