Gender and Health Hub, United Nations University- International Institute for Global Health, Kuala Lumpur, Malaysia.
GENDRO, Geneva, Switzerland.
Hum Vaccin Immunother. 2022 Dec 31;18(1):2035142. doi: 10.1080/21645515.2022.2035142. Epub 2022 Feb 10.
The influence of sex and gender in immune response and vaccine outcomes is established in many disease areas, including in COVID-19. Yet, there are notable gaps in the consideration of sex and gender in the analysis and reporting of COVID-19 vaccines clinical trial data. The push for stronger sex and gender integration in vaccines science should be championed by all researchers and stakeholders across the R&D and access ecosystem - not just gender experts. This requires joint action on the tactical framing of customized value propositions (based on stakeholder motivations), the stronger enforcement of existing regulation, tools, and commitments, and aligning the overall agenda to parallel calls on intersectionality, equity diversity and inclusion.
在许多疾病领域，包括 COVID-19 中，性别对免疫反应和疫苗效果的影响已得到证实。然而，在分析和报告 COVID-19 疫苗临床试验数据时，对性别的考虑存在明显差距。应该由研发和获取生态系统中的所有研究人员和利益相关者——而不仅仅是性别专家——倡导在疫苗科学中加强性别平等。这需要联合采取行动，制定定制价值主张的战术框架（基于利益相关者的动机），加强现有法规、工具和承诺的执行力度，并调整总体议程，以呼应交叉性、公平性、多样性和包容性的呼吁。
