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蛋白质摄入量和肾功能对肾功能损害患者及肾移植后患者血浆氨基酸的影响。

Influence of protein intake and renal function on plasma amino acids in patients with renal impairment and after kidney transplantation.

作者信息

Pechar J, Málek P, Doberský P, Skála I, Jirka J, Schück O, Nádvorniková H, Reneltová I

出版信息

Nutr Metab. 1978;22(5):278-87.

PMID:351466
Abstract

A group of 17 patients with chronic renal impairment and a group of 11 patients surviving for 3--7 years after kidney transplantation were examined. In all patients plasma amino acids were analyzed. The ratio of essential/nonessential amino acids, the valine/glycine ratio and Whitehead's quotient are influenced above all by the dietary protein intake. Raised citrulline and 3-methylhistidine values were not influenced by the protein intake, while they correlate with indicators of renal function. Changes detected after kidney transplantation are analogous.

摘要

对一组17例慢性肾功能损害患者和一组11例肾移植后存活3至7年的患者进行了检查。对所有患者的血浆氨基酸进行了分析。必需氨基酸/非必需氨基酸的比例、缬氨酸/甘氨酸比例和怀特黑德商数首先受膳食蛋白质摄入量的影响。瓜氨酸和3-甲基组氨酸值升高不受蛋白质摄入量影响,但与肾功能指标相关。肾移植后检测到的变化类似。

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