Department of Chemistry, School of Physical Sciences, Shah Jalal University of Science and Technology, 3114, Sylhet, Bangladesh.
Center of Excellence for Advanced Materials Research (CEAMR) & Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, 21589, Jeddah, Saudi Arabia.
Chem Rec. 2022 Jul;22(7):e202100331. doi: 10.1002/tcr.202100331. Epub 2022 Feb 10.
Metal-based nanoparticles are very promising for their applications in cancer diagnosis, drug delivery and therapy. Breast cancer is the major reason of death in woman especially in developed countries including EU and USA. Due to the heterogeneity of cancer cells, nanoparticles are effective as therapeutics and diagnostics. Anti-cancer therapy of breast tumors is challenging because of highly metastatic progression of the disease to brain, bone, lung, and liver. Magnetic nanoparticles are crucial for metastatic breast cancer detection and protection. This review comprehensively discusses the application of nanomaterials as breast cancer therapy, therapeutics, and diagnostics.
基于金属的纳米粒子在癌症诊断、药物输送和治疗方面的应用具有广阔的前景。乳腺癌是女性，特别是包括欧盟和美国在内的发达国家女性死亡的主要原因。由于癌细胞的异质性，纳米粒子作为治疗剂和诊断剂非常有效。由于乳腺癌向脑、骨、肺和肝转移的高度进展，乳腺癌的治疗具有挑战性。磁性纳米粒子对于转移性乳腺癌的检测和保护至关重要。本文全面讨论了纳米材料作为乳腺癌治疗、治疗和诊断的应用。
