Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Republic of Korea.
Department of Pathology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Republic of Korea.
Medicine (Baltimore). 2022 Feb 11;101(6):e28808. doi: 10.1097/MD.0000000000028808.
Apocrine carcinoma is a rare malignant sweat gland tumor that has been reported in approximately 200 cases. This tumor usually occurs in the axilla, but in rare cases, it can also develop in the scalp. In the present work, we report 2 cases of cutaneous apocrine carcinoma of the scalp.
Two men visited our outpatient clinic with recurrence of tumor after undergoing surgery for scalp tumor at another hospital.
Brain magnetic resonance imaging of a 56-year old man showed the presence of a 5.0 × 4.5 × 4.4 cm scalp mass in the right parietal region, invading the skull and dura mater and a 2.2 × 2.0 × 0.7 cm bony mass without any skin lesions right next to the scalp mass. Neck magnetic resonance imaging of a 76-year-old man revealed the presence of a well-defined oval mass in the subcutaneous layer of the left occipital scalp and 2 enlarged lymph nodes in the left neck. Definite diagnoses were made postoperatively. The patients were diagnosed with cutaneous apocrine carcinoma. The diagnosis was confirmed through histopathological and immunohistochemical staining tests.
The tumors were removed with a wide safety margin and reconstructive surgery was performed.
Additional radiotherapy or chemotherapy was performed. Follow-up more than 6 months revealed no recurrence or metastasis.
If accurate diagnosis and treatment had taken place at the initial stages of the primary cutaneous apocrine carcinoma, it would have been possible to prevent recurrence and intracranial invasion. As recurrent primary cutaneous apocrine carcinoma can become aggressive and difficult to treat, even a small mass on the scalp must be evaluated carefully and treated properly.
大汗腺癌是一种罕见的恶性汗腺肿瘤，大约有 200 例报道。这种肿瘤通常发生在腋窝，但在罕见情况下，也可发生在头皮。在本研究中，我们报告了 2 例头皮大汗腺癌病例。
2 名男性因在另一家医院行头皮肿瘤手术后肿瘤复发，前来我院门诊就诊。
56 岁男性的颅脑磁共振成像显示右顶叶有一 5.0×4.5×4.4cm 的头皮肿块，侵犯颅骨和硬脑膜，紧邻头皮肿块右侧有一 2.2×2.0×0.7cm 的骨肿块，无皮肤病变。76 岁男性的颈部磁共振成像显示左枕头皮皮下层有一界限清楚的椭圆形肿块，左颈部有 2 个增大的淋巴结。术后明确诊断。患者被诊断为皮肤大汗腺癌。通过组织病理学和免疫组织化学染色试验确诊。
肿瘤广泛安全切除并进行了重建手术。
进行了额外的放疗或化疗。随访 6 个月以上未见复发或转移。
如果在原发性皮肤大汗腺癌的早期阶段进行准确的诊断和治疗，就有可能防止复发和颅内侵犯。由于复发性原发性皮肤大汗腺癌可能变得侵袭性更强且难以治疗，因此即使头皮上有小肿块也必须仔细评估并进行适当治疗。
