Shepherd Brandon, Spankovich Christopher, Bishop Charles E, Su Dan, Valle Karen, Schweinfurth John
Department of Otolaryngology and Communicative Sciences.
Department of Data Science.
Otol Neurotol. 2022 Mar 1;43(3):295-303. doi: 10.1097/MAO.0000000000003359.
There are limited population-based studies of central auditory processing (CAP). We aimed to determine the relationship between CAP measures and perceived hearing difficulty (PHD) despite normal pure-tone audiometry in an African-American population.
Cross-sectional.
Jackson Heart Study (JHS), Jackson, MS.
Participants of an African-American cohort (26% men; age 54.2, standard deviations [SD] 9.2) who self-reported hearing difficulty despite normal hearing sensitivity defined as audiometric pure-tone average (PTA-4: average of 500, 1000, 2000, and 4000 Hz) less than or equal to 25 dBHL (n = 911) or across all tested frequencies (PT-AF: 250-8000 Hz) less than or equal to 25 dBHL (n = 516).
The Quick Speech-in-Noise (QuickSIN) and Dichotic Digits, Double Pairs (DDT2) tests were used to assess CAP. Logistic regression was used to examine the association between measures of CAP and PHD; adjusted for age, sex, education, and pure tone audiogram.
PHD was present in 251 (28%) and 137 (27%) of participants using the PTA-4 and PT-AF models, respectively. Fully adjusted regression models revealed that each one-point increase in QuickSIN increased the odds of reporting PHD by 13.7% (odds ratio [OR] 1.14, p < 0.01, 95% CI: 1.08, 1.19) using the PTA-4 model and 15.0% (OR 1.15, p < 0.01, 95% CI: 1.08, 1.23) using the PT-AF model. For DDT2 testing, each 1% reduction in score, increased the odds of reporting PHD by 7.7% (OR 0.92, p < 0.01, 95% CI: 0.88, 0.97) in a fully adjusted PTA-4 model and 6.6% (OR 0.93, p = 0.04, 95% CI: 0.87, 0.99) in the PT-AF model.
CAP deficits were associated with increased odds of PHD in normal hearing participants within the JHS cohort.
基于人群的中枢听觉处理（CAP）研究有限。我们旨在确定非裔美国人中，尽管纯音听力测定正常，但CAP测量值与感知听力困难（PHD）之间的关系。
横断面研究。
密西西比州杰克逊市的杰克逊心脏研究（JHS）。
一个非裔美国人队列的参与者（26%为男性；年龄54.2岁，标准差[SD]9.2），他们自我报告有听力困难，尽管听力敏感度正常，定义为听力计纯音平均听阈（PTA - 4：500、1000、2000和4000赫兹的平均值）小于或等于25分贝听力级（dBHL）（n = 911），或所有测试频率（PT - AF：250 - 8000赫兹）小于或等于25 dBHL（n = 516）。
使用快速噪声言语测试（QuickSIN）和双耳数字对测试（DDT2）来评估CAP。采用逻辑回归分析CAP测量值与PHD之间的关联；对年龄、性别、教育程度和纯音听力图进行了校正。
分别使用PTA - 4和PT - AF模型时，251名（28%）和137名（27%）参与者存在PHD。完全校正的回归模型显示，使用PTA - 4模型时，QuickSIN每增加1分，报告PHD的几率增加13.7%（优势比[OR]1.14，p < 0.01，95%置信区间：1.08，1.19）；使用PT - AF模型时增加15.0%（OR 1.15，p < 0.01，95%置信区间：1.08，1.23）。对于DDT2测试，在完全校正的PTA - 4模型中，分数每降低1%，报告PHD的几率增加7.7%（OR 0.92，p < 0.01，95%置信区间：0.88，0.97）；在PT - AF模型中增加6.6%（OR 0.93，p = 0.04，95%置信区间：0.87，0.99）。
在JHS队列中，听力正常的参与者中，CAP缺陷与PHD几率增加相关。
