Haas Patrick J, Bishop Charles E, Gao Yan, Griswold Michael E, Schweinfurth John M
Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson, Mississippi.
Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, Mississippi, U.S.A.
Laryngoscope. 2016 Oct;126(10):2376-81. doi: 10.1002/lary.25924. Epub 2016 Mar 1.
OBJECTIVES/HYPOTHESIS: To evaluate the relationships among measures of physical activity and hearing in the Jackson Heart Study.
Prospective cohort study.
We assessed hearing on 1,221 Jackson Heart Study participants who also had validated physical activity questionnaire data on file. Hearing thresholds were measured across frequency octaves from 250 to 8,000 Hz, and various frequency pure-tone averages (PTAs) were constructed, including PTA4 (average of 500, 1,000, 2,000, and 4,000 Hz), PTA-high (average of 4,000 and 8,000 Hz), PTA-mid (average of 1,000 and 2,000 Hz), and PTA-low (average of 250 and 500 Hz). Hearing loss was defined for pure tones and pure-tone averages as >25 dB HL in either ear and averaged between the ears. Associations between physical activity and hearing were estimated using linear regression, reporting changes in decibel hearing level, and logistic regression, reporting odds ratios (OR) of hearing loss.
Physical activity exhibited a statistically significant but small inverse relationship with PTA4, -0.20 dB HL per doubling of activity (95% confidence interval [CI]: -0.35, -0.04; P = .016), as well as with PTA-low and pure tones at 250, 2,000, and 4,000 Hz in adjusted models. Multivariable logistic regression modeling supported a decrease in the odds of high-frequency hearing loss among participants who reported at least some moderate weekly physical activity (PTA-high, OR: 0.69 [95% CI: 0.52, 0.92]; P = .011 and 4000 Hz, OR: 0.75 [95% CI: 0.57, 0.99]; P = .044).
Our study provides further evidence that physical activity is related to better hearing; however, the clinical significance of this relationship cannot be estimated given the nature of the cross-sectional study design.
2b Laryngoscope, 126:2376-2381, 2016.
目的/假设：在杰克逊心脏研究中评估身体活动指标与听力之间的关系。
前瞻性队列研究。
我们对1221名杰克逊心脏研究参与者进行了听力评估，这些参与者也有经过验证的身体活动问卷数据存档。在250至8000赫兹的频率倍频程上测量听力阈值，并构建各种频率的纯音平均值（PTA），包括PTA4（500、1000、2000和4000赫兹的平均值）、PTA-高（4000和8000赫兹的平均值）、PTA-中（1000和2000赫兹的平均值）以及PTA-低（250和500赫兹的平均值）。纯音和纯音平均值的听力损失定义为任一耳>25分贝听力级（dB HL），并取两耳平均值。使用线性回归估计身体活动与听力之间的关联，报告听力水平分贝的变化，以及使用逻辑回归报告听力损失的比值比（OR）。
身体活动与PTA4呈现出统计学上显著但较小的负相关，活动量每增加一倍，听力水平下降0.20 dB HL（95%置信区间[CI]：-0.35，-0.04；P = 0.016），在调整模型中，与PTA-低以及250、2000和4000赫兹的纯音也呈现负相关。多变量逻辑回归模型支持报告每周至少有一些适度身体活动的参与者高频听力损失几率降低（PTA-高，OR：0.69 [95% CI：0.52，0.92]；P = 0.011；4000赫兹，OR：0.75 [95% CI：0.57，0.99]；P = 0.044）。
我们的研究提供了进一步证据表明身体活动与更好的听力有关；然而，鉴于横断面研究设计的性质，无法估计这种关系的临床意义。
2b 喉镜，126:2376 - 2381，2016年。
