Faculty of Mathematics and Computer Science, University of Münster, Münster, Germany.
Department of Ophthalmology, St. Franziskus-Hospital, Münster, Germany.
Transl Vis Sci Technol. 2022 Feb 1;11(2):21. doi: 10.1167/tvst.11.2.21.
The purpose of this study is to describe and quantify the nonpathological axial stretching in the retinal vascular plexus in three-dimensional (3D) optical coherence tomography angiography (OCTA) images.
The 3D vascular network underneath the inner limiting membrane of OCTA volumes was labeled as ground truth (GT) data. To analyze the cross-section area of the vessels the width and depth of the vessels in the GT data were computed and an elliptical quotient was proposed to quantify the axial stretching.
A total of 21 3D OCTA volumes were labeled. It was found that the vessels in 3D OCTA images are stretched in the direction of the A-Scan by a factor of 2.46 ± 1.82 with a median of 2.24. Furthermore, a larger cross-section area leads to higher axial stretching.
The elliptical shape of the cross-section area of the vessel does not match with the expected pathology of the vascular network in the human eye. Therefore a correction of the volume data before a 3D analysis is recommended.
This work gives a systematic insight to the stretched shape of vessels in 3D OCTA images and is relevant for further clinical research analyzing the 3D vascular network.
本研究旨在描述和量化三维（3D）光相干断层扫描血管造影（OCTA）图像中视网膜血管丛的非病理性轴向拉伸。
将 OCTA 容积内的内界膜下的 3D 血管网络标记为真实数据（GT）。为了分析血管的横截面积，计算了 GT 数据中血管的宽度和深度，并提出了椭圆商来量化轴向拉伸。
共标记了 21 个 3D OCTA 容积。结果发现，3D OCTA 图像中的血管在 A 扫描方向上被拉伸了 2.46±1.82 倍，中位数为 2.24。此外，较大的横截面积会导致更高的轴向拉伸。
血管横截面积的椭圆形状与人类眼睛中血管网络的预期病理不符。因此，建议在进行 3D 分析之前对体积数据进行校正。
翻译的准确性可能会受到多种因素的影响，包括原文的清晰度、语法结构、词汇选择和语言习惯等。如果你对翻译结果有任何疑问或需要进一步的解释，请随时告诉我。
