College of Chemistry, Changchun Normal University, Changchun, 130032, People's Republic of China.
Mikrochim Acta. 2022 Feb 12;189(3):99. doi: 10.1007/s00604-022-05207-7.
For the first time it is demonstrated that zeolitic imidazolate framework-8 electrospun nanofibers (ZIF-8 NF) could serve as electrochemiluminescence (ECL) accelerator for the facile detection of terbutaline residual. A novel ECL sensor for the determination of terbutaline was fabricated based on ZIF-8 NF. The ZIF-8 NF were successfully prepared according to electrospinning and in-situ growth method. First, chitosan was modified on the surface of the electrode, and then the ZIF-8 NF was modified onto the upper layer of the chitosan. Taking advantages of chitosan and ZIF-8 NF in conductivity and electrocatalysis, the modified electrode presents obvious ECL phenomenon in 0.2 M PBS solution (pH 10.0) containing 0.025 M luminol. After the addition of terbutaline, ECL intensity decreased significantly, and the decreasing value showed a linear relationship with the logarithm of terbutaline concentration. The linear range was from 2.0 × 10 to 2.0 × 10 M, and the detection limit was 1.41 × 10 M (3σ/m). The method had high sensitivity, good stability, and good applicability to actual pork samples.
首次证明沸石咪唑酯骨架-8 电纺纳米纤维（ZIF-8 NF）可用作电致化学发光（ECL）加速剂，以简便检测特布他林残留。基于 ZIF-8 NF 构建了用于测定特布他林的新型 ECL 传感器。根据静电纺丝和原位生长法成功制备了 ZIF-8 NF。首先，壳聚糖修饰在电极表面，然后将 ZIF-8 NF 修饰在壳聚糖的上层。利用壳聚糖和 ZIF-8 NF 的导电性和电催化性，修饰电极在含有 0.025 M 鲁米诺的 0.2 M PBS 溶液（pH 10.0）中呈现出明显的 ECL 现象。加入特布他林后，ECL 强度显著降低，且降低值与特布他林浓度的对数呈线性关系。线性范围为 2.0×10 至 2.0×10 M，检测限为 1.41×10 M（3σ/m）。该方法具有高灵敏度、良好的稳定性，且对实际猪肉样品具有良好的适用性。
