Wren B G, Brown L B
Med J Aust. 1986 Mar 31;144(7):369-70. doi: 10.5694/j.1326-5377.1986.tb115924.x.
A double-blind crossover study that compared clonidine and a placebo, which were administered to 19 postmenopausal women who were suffering from hot flushes, failed to demonstrate any statistical reduction in the number of hot flushes. Therefore, clonidine is not recommended as a treatment drug for this symptom.
一项双盲交叉研究对19名患有潮热的绝经后女性给予可乐定和安慰剂进行比较,结果未能显示潮热次数有任何统计学上的减少。因此,不建议将可乐定作为治疗该症状的药物。