染色体级别的基因组为植物药物生物合成提供了线索。

Chromosome-scale genomes throw light on plant drug biosynthesis.

机构信息

Biomolécules et Biotechnologies Végétales, BBV, EA2106, Université de Tours, Tours, France.

Limagrain, Centre de Recherche, Route d'Ennezat, Chappes, France.

出版信息

Trends Pharmacol Sci. 2022 Jul;43(7):542-545. doi: 10.1016/j.tips.2022.01.007. Epub 2022 Feb 9.

DOI:10.1016/j.tips.2022.01.007

PMID:35151502

Abstract

Recent chromosome-scale genomes from prominent medicinal plants have provided unprecedented insight into the architecture and evolution of some prominent metabolic pathways. These new technologies also facilitate the identification of plant drug biosynthetic genes and would likely accelerate the development of new bioengineering procedures to secure the supply of important plant-derived pharmaceuticals.

摘要

近年来，一些重要药用植物的染色体水平基因组为一些重要代谢途径的结构和进化提供了前所未有的见解。这些新技术还有助于鉴定植物药物生物合成基因，并可能加速开发新的生物技术程序，以确保重要植物来源药物的供应。