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下颌骨中心性巨细胞病变的治疗。

Treatment of a central giant cell lesion in the mandible.

作者信息

Lima Bernardo Correia, Pinheiro Giulianna Lima, Pinto Leonardo Augustus Peral Ferreira, Cavalcante Maria Aparecida de Albuquerque

机构信息

Department of Oral Surgery, Oral Surgery Service, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Natl J Maxillofac Surg. 2021 Sep-Dec;12(3):414-417. doi: 10.4103/njms.NJMS_227_20. Epub 2021 Dec 13.

DOI:10.4103/njms.NJMS_227_20
PMID:35153441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8820298/
Abstract

Central giant cell lesion (CGCL) is a benign intraosseous lesion that usually accompany the gnathic bones in the anterior region, mostly crossing the midline. Its clinical features involve cortical expansion, tooth displacement, and root resorption. Pain may occur in 20% of cases. Histopathological characteristics are like other pathological entities, being necessary discarding them. In this case, a 53-year-old female presented an expansive legion in the anterior mandible with tooth displacement and pain. After incisional biopsy, the result was CGCL. Surgical planning involved manufacturing a biomodel, bending the reconstruction plate to give the correct mandibular arch perimeter. After that, it was performed a segmental resection and installation of a reconstruction plate using a cervical approach. The patient is under follow-up with no signs of recurrence or complications.

摘要

中央巨细胞病变(CGCL)是一种良性骨内病变,通常发生于前部颌骨,大多跨越中线。其临床特征包括皮质膨胀、牙齿移位和牙根吸收。20%的病例可能会出现疼痛。组织病理学特征与其他病理实体相似,因此有必要将它们排除。在本病例中,一名53岁女性在前下颌骨出现一个膨胀性病变,并伴有牙齿移位和疼痛。切开活检后,结果为CGCL。手术规划包括制作一个生物模型,弯曲重建钢板以获得正确的下颌弓周长。之后,采用颈部入路进行节段性切除并安装重建钢板。患者正在接受随访,没有复发或并发症的迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/3a83aa69a3b4/NJMS-12-414-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/3f6b26982bce/NJMS-12-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/2531a1cf46c4/NJMS-12-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/69ae0ebca1dd/NJMS-12-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/8a88be2959d5/NJMS-12-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/c543ea570fda/NJMS-12-414-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/3a83aa69a3b4/NJMS-12-414-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/3f6b26982bce/NJMS-12-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/2531a1cf46c4/NJMS-12-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/69ae0ebca1dd/NJMS-12-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/8a88be2959d5/NJMS-12-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/c543ea570fda/NJMS-12-414-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5360/8820298/3a83aa69a3b4/NJMS-12-414-g006.jpg

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本文引用的文献

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Clinical factors associated with the recurrence of central giant cell lesions.与中央性颌骨 giant cell 病变复发相关的临床因素。
J Oral Pathol Med. 2019 Oct;48(9):799-802. doi: 10.1111/jop.12937. Epub 2019 Aug 12.
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An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature.儿童患者侵袭性中央性骨巨细胞瘤:病例报告及文献复习。
J Otolaryngol Head Neck Surg. 2019 Jul 18;48(1):32. doi: 10.1186/s40463-019-0356-5.
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Central giant cell lesion of the jaws: An updated analysis of 2270 cases reported in the literature.
颌骨中央性巨型细胞瘤:文献报道 2270 例病例的更新分析。
J Oral Pathol Med. 2018 Sep;47(8):731-739. doi: 10.1111/jop.12730. Epub 2018 May 29.
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