Vohra Lubna M, Jabeen Dua, Khan Nargis, Nizar Azmeena, Jamil Anum, Siddiqui Tariq
Department of Breast Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Ann Med Surg (Lond). 2022 Feb;74:103342. doi: 10.1016/j.amsu.2022.103342. Epub 2022 Feb 5.
The emergence of coronavirus disease 2019 (COVID-19) pandemic has crippled the healthcare systems all over the world. Cancer treatment is indispensable and disruption in its provision can lead to unanticipated consequences. No local data exists that has quantified the impact of COVID-19 pandemic on breast cancer surgery in a lower middle-income country (LMIC), therefore, the present retrospective comparative cohort study is directed to determine the trends in breast surgery operative volumes and its outcomes at our institution in Pakistan.
Data was collected retrospectively from Pre-COVID-19 and COVID-19 era to determine impact of the current pandemic on breast cancer management practices and outcomes.
Cohort results showed a decline in the number of surgeries during COVID-19 era. A total 149 cases were operated during study period vs. 231 during same Pre-COVID-19 i.e. a 35.5% drop in cancer surgeries. In early COVID-19 time frame, only 4 patients had breast reconstruction, 12 out of 149 (8.05%) surgical candidates were identified having positive COVID-19 status preoperatively and one ASA class 3 patient caught COVID-19 post-surgery and succumbed to virus.
Pandemic has a negative effect on cancer management in a LMIC with compromised access and care of cancer patients.
2019年冠状病毒病（COVID-19）大流行的出现使世界各地的医疗系统陷入瘫痪。癌症治疗不可或缺，其供应中断可能导致意想不到的后果。在低收入和中等收入国家（LMIC），尚无量化COVID-19大流行对乳腺癌手术影响的本地数据，因此，本回顾性比较队列研究旨在确定巴基斯坦我们机构的乳腺癌手术量趋势及其结果。
回顾性收集COVID-19之前和COVID-19时期的数据，以确定当前大流行对乳腺癌管理实践和结果的影响。
队列结果显示，COVID-19时期手术数量有所下降。研究期间共进行了149例手术，而在COVID-19之前的同一时期为231例，即癌症手术下降了35.5%。在COVID-19早期阶段，只有4例患者进行了乳房重建，149例手术候选者中有12例（8.05%）术前COVID-19检测呈阳性，1例ASA 3级患者术后感染COVID-19并死于该病毒。
在一个癌症患者获得治疗的机会和护理受限的低收入和中等收入国家，大流行对癌症管理产生了负面影响。
