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本文引用的文献

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Conducting phase 1 cancer clinical trials during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related disease pandemic.在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)相关疾病大流行期间开展1期癌症临床试验。
Eur J Cancer. 2020 Jun;132:8-10. doi: 10.1016/j.ejca.2020.03.023. Epub 2020 Apr 6.
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Commentary on Ferguson, et al., "Impact of Non-pharmaceutical Interventions (NPIs) to Reduce COVID-19 Mortality and Healthcare Demand".评 Ferguson 等人的“减少 COVID-19 死亡率和医疗需求的非药物干预(NPIs)的影响”一文。
Bull Math Biol. 2020 Apr 8;82(4):52. doi: 10.1007/s11538-020-00726-x.
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Cancer guidelines during the COVID-19 pandemic.2019冠状病毒病大流行期间的癌症指南。
Lancet Oncol. 2020 May;21(5):629-630. doi: 10.1016/S1470-2045(20)30217-5. Epub 2020 Apr 2.
4
Essential care of critical illness must not be forgotten in the COVID-19 pandemic.在新冠疫情期间,危重症的基本护理绝不能被忽视。
Lancet. 2020 Apr 18;395(10232):1253-1254. doi: 10.1016/S0140-6736(20)30793-5. Epub 2020 Apr 1.
5
Cancer, COVID-19 and the precautionary principle: prioritizing treatment during a global pandemic.癌症、COVID-19 和预防原则:在全球大流行期间优先考虑治疗。
Nat Rev Clin Oncol. 2020 May;17(5):268-270. doi: 10.1038/s41571-020-0362-6.
6
International Guidelines on Radiation Therapy for Breast Cancer During the COVID-19 Pandemic.2019年冠状病毒病大流行期间乳腺癌放射治疗国际指南。
Clin Oncol (R Coll Radiol). 2020 May;32(5):279-281. doi: 10.1016/j.clon.2020.03.006.
7
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.抗凝治疗与伴有凝血功能障碍的严重 2019 冠状病毒病患者的死亡率降低相关。
J Thromb Haemost. 2020 May;18(5):1094-1099. doi: 10.1111/jth.14817. Epub 2020 Apr 27.
8
Fair Allocation of Scarce Medical Resources in the Time of Covid-19.新冠疫情期间稀缺医疗资源的公平分配
N Engl J Med. 2020 May 21;382(21):2049-2055. doi: 10.1056/NEJMsb2005114. Epub 2020 Mar 23.
9
Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China.新型冠状病毒肺炎(SARS-CoV-2)感染的癌症患者:一项中国全国性分析。
Lancet Oncol. 2020 Mar;21(3):335-337. doi: 10.1016/S1470-2045(20)30096-6. Epub 2020 Feb 14.
10
Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations.癌症患者在肿瘤治疗全程中心血管疾病的管理:ESMO 共识推荐。
Ann Oncol. 2020 Feb;31(2):171-190. doi: 10.1016/j.annonc.2019.10.023.

ESMO 管理和治疗适应 COVID-19 时代的建议:乳腺癌。

ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer.

机构信息

Institut Jules Bordet and l'Université Libre de Bruxelles (U.LB), Brussels, Belgium.

European Institute of Oncology (IEO) IRCCS, Milan, Italy.

出版信息

ESMO Open. 2020 May;5(Suppl 3):e000793. doi: 10.1136/esmoopen-2020-000793.

DOI:10.1136/esmoopen-2020-000793
PMID:32439716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7295852/
Abstract

The global preparedness and response to the rapid escalation to severe acute respiratory syndrome coronavirus (SARS-CoV)-2-related disease (COVID-19) to a pandemic proportion has demanded the formulation of a reliable, useful and evidence-based mechanism for health services prioritisation, to achieve the highest quality standards of care to all patients. The prioritisation of high value cancer interventions must be embedded in the agenda for the pandemic response, ensuring that no inconsistency or discrepancy emerge in the health planning processes.The aim of this work is to organise health interventions for breast cancer management and research in a tiered framework (high, medium, low value), formulating a scheme of prioritisation per clinical cogency and intrinsic value or magnitude of benefit. The public health tools and schemes for priority setting in oncology have been used as models, aspiring to capture clinical urgency, value in healthcare, community goals and fairness, while respecting the principles of benevolence, non-maleficence, autonomy and justice.We discuss the priority health interventions across the cancer continuum, giving a perspective on the role and meaning to maintain some services (undeferrable) while temporarily abrogate some others (deferrable). Considerations for implementation and the essential link to pre-existing health services, especially primary healthcare, are addressed, outlining a framework for the development of effective and functional services, such as telemedicine.The discussion covers the theme of health systems strategising, and why oncology care, in particular breast cancer care, should be maintained in parallel to pandemic control measures, providing a pragmatic clinical model within the broader context of public healthcare schemes.

摘要

全球对严重急性呼吸系统综合症冠状病毒(SARS-CoV-2)相关疾病(COVID-19)迅速升级至大流行规模的准备和应对,要求制定一种可靠、有用和基于证据的卫生服务优先排序机制,以实现对所有患者的最高质量标准的护理。高价值癌症干预措施的优先排序必须纳入大流行应对议程,确保在卫生规划过程中不会出现不一致或差异。

这项工作的目的是在分层框架(高、中、低价值)中组织乳腺癌管理和研究的卫生干预措施,根据临床相关性和内在价值或受益程度制定优先排序方案。公共卫生工具和肿瘤学中的优先排序方案已被用作模型,旨在捕捉临床紧迫性、医疗保健中的价值、社区目标和公平性,同时尊重仁爱、不伤害、自主和正义的原则。

我们讨论了贯穿整个癌症的优先卫生干预措施,从维持某些服务(不可推迟)和暂时放弃某些服务(可推迟)的角度探讨了其作用和意义。考虑了实施的考虑因素以及与现有卫生服务的重要联系,特别是初级卫生保健,概述了发展有效和功能性服务的框架,如远程医疗。

讨论涵盖了卫生系统战略制定的主题,以及为什么肿瘤学护理,特别是乳腺癌护理,应该与大流行控制措施并行进行,在更广泛的公共医疗保健计划背景下提供实用的临床模式。