Yamauchi H, Sunamura M, Takeda K, Suzuki T, Itoh K, Miyagawa K
Tohoku J Exp Med. 1986 Feb;148(2):197-205. doi: 10.1620/tjem.148.197.
A 23 year old pregnant woman presented in her third trimester with severe pancreatitis and hyperlipidemia. Initial investigations suggested that her pancreatitis was induced by profound hypertriglyceridemia, which was the result of an underlying Fredrickson's V type hyperlipoproteinemia exacerbated by pregnancy. Concern for the life of the fetus prompted a caesarean operation and then drainage procedure for pancreatitis. Plasma exchange, carried out to lower the levels of lipids and the pancreatic enzymes, improved the signs and symptoms of the patient. Plasma exchange may be of great use in the management of hyperlipidemic pancreatitis.
一名23岁的孕妇在孕晚期出现了严重的胰腺炎和高脂血症。初步检查表明,她的胰腺炎是由严重的高甘油三酯血症引起的,而高甘油三酯血症是由潜在的弗雷德里克森V型高脂蛋白血症在孕期加重所致。出于对胎儿生命的担忧,实施了剖宫产手术,随后对胰腺炎进行了引流手术。为降低血脂和胰腺酶水平而进行的血浆置换改善了患者的体征和症状。血浆置换在高脂血症性胰腺炎的治疗中可能非常有用。