Saravanan P, Blumenthal S, Anderson C, Stein R, Berkelhammer C
Department of Internal Medicine, Christ Hospital and Medical Center, Oak Lawn, Illinois, USA.
J Clin Gastroenterol. 1996 Jun;22(4):295-8. doi: 10.1097/00004836-199606000-00011.
We describe the response to plasma exchange in a woman with extreme gestational hyperlipidemia and severe pancreatitis. Her serum triglyceride reached an astounding level of 21,300 mg/dl-among the highest concentrations ever recorded. Two consecutive plasma exchanges led to a remarkable reduction in triglyceride levels of 73% and 82%, respectively. Plasma viscosity decreased by 50% after the first plasma exchange. This was associated with an equally dramatic and unexpectedly rapid resolution of severe pancreatitis. Plasma exchange can rapidly and safely resolve extreme hyperlipidemia and be associated with prompt resolution of pancreatitis in women with severe gestational hyperlipidemic pancreatitis.
我们描述了一位患有极重度妊娠高脂血症和重症胰腺炎的女性对血浆置换的反应。她的血清甘油三酯水平达到了惊人的21300mg/dl,这是有记录以来的最高浓度之一。连续两次血浆置换分别使甘油三酯水平显著降低了73%和82%。第一次血浆置换后血浆黏度降低了50%。这与重症胰腺炎同样显著且出乎意料的快速缓解相关。血浆置换可以快速、安全地解决极重度高脂血症,并与重症妊娠高脂血症性胰腺炎女性的胰腺炎迅速缓解相关。