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提高茶多酚生物利用度的纳米策略:制备、应用及挑战

Nano-Strategies for Enhancing the Bioavailability of Tea Polyphenols: Preparation, Applications, and Challenges.

作者信息

Niu Li, Li Ziqiang, Fan Wei, Zhong Xiaohong, Peng Miao, Liu Zhonghua

机构信息

Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China.

National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, China.

出版信息

Foods. 2022 Jan 29;11(3):387. doi: 10.3390/foods11030387.

DOI:10.3390/foods11030387
PMID:35159537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8834201/
Abstract

Tea polyphenols (TPs) are among the most abundant functional compounds in tea. They exhibit strong antioxidant, anti-inflammatory, and anti-cancer effects. However, their instability and low bioavailability limits their applications. Nanotechnology, which involves the use of nanoscale substances (sizes ranging from 1 to 100 nm) to improve the properties of substances, provides a solution for enhancing the stability and bioavailability of TPs. We reviewed the preparation, performance, effects, and applications of different types of TPs nanocarriers. First, we introduced the preparation of different nanocarriers, including nanoparticles, nanoemulsions, nanomicelles, and nanolipids. Then, we discussed various applications of tea polyphenol-loaded nanocarriers in functional ingredient delivery, food quality improvement, and active food packaging. Finally, the challenges and future development directions of TPs nanocarriers were elucidated. In conclusion, a nano-strategy may be the "key" to break the application barriers of TPs. Therefore, the use of nano-strategies for the safe, stable, and efficient release of TPs is the direction of future research.

摘要

茶多酚(TPs)是茶叶中含量最为丰富的功能化合物之一。它们具有强大的抗氧化、抗炎和抗癌作用。然而,其不稳定性和低生物利用度限制了它们的应用。纳米技术涉及使用纳米级物质(尺寸范围为1至100纳米)来改善物质的性能,为提高茶多酚的稳定性和生物利用度提供了一种解决方案。我们综述了不同类型的茶多酚纳米载体的制备、性能、作用及应用。首先,我们介绍了不同纳米载体的制备,包括纳米颗粒、纳米乳液、纳米胶束和纳米脂质体。然后,我们讨论了负载茶多酚的纳米载体在功能成分递送、食品品质改善和活性食品包装等方面的各种应用。最后,阐明了茶多酚纳米载体面临的挑战和未来发展方向。总之,纳米策略可能是打破茶多酚应用障碍的“关键”。因此,利用纳米策略实现茶多酚的安全、稳定和高效释放是未来的研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/33a36e9bc70e/foods-11-00387-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/70bcca67278f/foods-11-00387-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/c41021cc0910/foods-11-00387-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/ad53dd25e897/foods-11-00387-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/33a36e9bc70e/foods-11-00387-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/70bcca67278f/foods-11-00387-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/c41021cc0910/foods-11-00387-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/ad53dd25e897/foods-11-00387-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/8834201/33a36e9bc70e/foods-11-00387-g004.jpg

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