经典免疫抑制剂、维甲酸类药物和生物制剂治疗化脓性汗腺炎的疗效与毒性
Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa.
作者信息
Das Kinnor, Daveluy Steven, Kroumpouzos George, Agarwal Komal, Podder Indrashis, Farnbach Katherine, Ortega-Loayza Alex G, Szepietowski Jacek C, Grabbe Stephan, Goldust Mohamad
机构信息
Department of Dermatology Venereology and Leprosy, Silchar Medical College, Silchar 788014, India.
Department of Dermatology, Wayne State University, Detroit, MI 48202, USA.
出版信息
J Clin Med. 2022 Jan 27;11(3):670. doi: 10.3390/jcm11030670.
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified articles.
化脓性汗腺炎（HS）是一种以反复发作为特征的顶泌汗腺慢性炎症性疾病。虽然有多种治疗方法，但尚无一种能完全治愈。已经对几种免疫抑制剂进行了研究，结果令人鼓舞且有针对性的治疗方法。在本综述中，我们重点介绍了用于这种疾病的各种免疫抑制剂及其显著特点，以使医生能够为患者选择正确的治疗方法。对同行评审文献的检索包括临床试验、科学综述、病例系列、病例报告和指南。文献通过电子数据库（MEDLINE和PubMed）检索至2021年11月；从已识别文章的参考文献中纳入了其他文章。
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