弗里克-XO-普朗尼克F-127放射变色剂量计的最佳组成和储存条件研究

Study of the Optimal Composition and Storage Conditions of the Fricke-XO-Pluronic F-127 Radiochromic Dosimeter.

作者信息

Piotrowski Michał, Maras Piotr, Kadłubowski Sławomir, Kozicki Marek

机构信息

Department of Mechanical Engineering, Informatics and Chemistry of Polymer Materials, Faculty of Materials Technologies and Textile Design, Lodz University of Technology, 90-543 Lodz, Poland.

Department of Radiotherapy Planning, Copernicus Hospital, 93-513 Lodz, Poland.

出版信息

Materials (Basel). 2022 Jan 27;15(3):984. doi: 10.3390/ma15030984.

DOI:10.3390/ma15030984

PMID:35160929

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8838533/

Abstract

This paper presents the results of research on the Fricke-XO-Pluronic F-127 dosimeter. It consists of a Fricke dosimetric solution and xylenol orange (XO), which are embedded in a matrix of poly(ethylene oxide)--poly(propylene oxide)--poly(ethylene oxide) (Pluronic F-127). Upon irradiation, Fe ions transform into Fe, forming a colored complex with XO ([XO-Fe]). The color intensity is related to the dose absorbed. The optimal composition, storage conditions, and radiation-induced performance of the Fricke-XO-Pluronic F-127 dosimeter were investigated. The optimal composition was found to be 1 mM FAS, 50 mM sulfuric acid (HSO), 0.165 mM XO in 25% Pluronic F-127. The basic features of this dosimeter are discussed, such as dose sensitivity, linear and dynamic dose range, stability before and after irradiation, storage conditions, dose response for irradiation with 6 and 15 MV photons, and batch-to-batch reproducibility. The obtained results showed a certain potential of the Fricke-XO-Pluronic F-127 for radiotherapy dosimetry.

摘要

本文介绍了对弗里克-XO-普朗尼克F-127剂量计的研究结果。它由弗里克剂量测定溶液和二甲酚橙（XO）组成，二者嵌入聚（环氧乙烷）-聚（环氧丙烷）-聚（环氧乙烷）（普朗尼克F-127）的基质中。辐照时，铁离子转变为铁，与XO形成有色络合物（[XO-Fe]）。颜色强度与吸收剂量相关。研究了弗里克-XO-普朗尼克F-127剂量计的最佳组成、储存条件和辐射诱导性能。发现最佳组成为25%普朗尼克F-127中含1 mM FAS、50 mM硫酸（HSO）、0.165 mM XO。讨论了该剂量计的基本特性，如剂量敏感性、线性和动态剂量范围、辐照前后的稳定性、储存条件、6和15 MV光子辐照的剂量响应以及批次间的重现性。所得结果表明弗里克-XO-普朗尼克F-127在放射治疗剂量测定方面具有一定潜力。